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-Structure paper
Title | X-Ray Structures of Torpedo Californica Acetylcholinesterase Complexed with (+)-Huperzine a and (-)-Huperzine B: Structural Evidence for an Active Site Rearrangement |
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Journal, issue, pages | Biochemistry, Vol. 41, Page 10810-, Year 2002 |
Publish date | Nov 6, 2000 (structure data deposition date) |
Authors | Dvir, H. / Jiang, H.L. / Wong, D.M. / Harel, M. / Chetrit, M. / He, X.C. / Jin, G.Y. / Yu, G.L. / Tang, X.C. / Silman, I. ...Dvir, H. / Jiang, H.L. / Wong, D.M. / Harel, M. / Chetrit, M. / He, X.C. / Jin, G.Y. / Yu, G.L. / Tang, X.C. / Silman, I. / Bai, D.L. / Sussman, J.L. |
External links | Biochemistry / PubMed:12196020 |
Methods | X-ray diffraction |
Resolution | 1.8 - 2.35 Å |
Structure data | PDB-1ea5: PDB-1gpk: PDB-1gpn: |
Chemicals | ChemComp-NAG: ChemComp-HOH: ChemComp-HUP: ChemComp-HUB: |
Source |
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Keywords | HYDROLASE / SERINE HYDROLASE / NEUROTRANSMITTER CLEAVAGE / CATALYTIC TRIAD / ALPHA/BETA HYDROLASE / CHOLINESTERASE / HUPERZINE A / ALZHEIMER'S DISEASE / HUPERZINE B |