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Structure paper

TitleCrystal structures of Giardia lamblia guanine phosphoribosyltransferase at 1.75 A(,).
Journal, issue, pagesBiochemistry, Vol. 39, Page 6781-6790, Year 2000
Publish dateJan 4, 2000 (structure data deposition date)
AuthorsShi, W. / Munagala, N.R. / Wang, C.C. / Li, C.M. / Tyler, P.C. / Furneaux, R.H. / Grubmeyer, C. / Schramm, V.L. / Almo, S.C.
External linksBiochemistry / PubMed:10841757
MethodsX-ray diffraction
Resolution1.75 Å
Structure data

PDB-1dqn:
CRYSTAL STRUCTURE OF GIARDIA GUANINE PHOSPHORIBOSYLTRANSFERASE COMPLEXED WITH A TRANSITION STATE ANALOGUE
Method: X-RAY DIFFRACTION / Resolution: 1.75 Å

PDB-1dqp:
CRYSTAL STRUCTURE OF GIARDIA GUANINE PHOSPHORIBOSYLTRANSFERASE COMPLEXED WITH IMMUCILLING
Method: X-RAY DIFFRACTION / Resolution: 1.75 Å

Chemicals

ChemComp-MG:
Unknown entry

ChemComp-IMU:
PHOSPHORIC ACID MONO-[5-(2-AMINO-4-OXO-4,5-DIHYDRO-3H-PYRROLO[3,2-D]PYRIMIDIN-7-YL)-3,4-DIHYDROXY-PYRROLIDIN-2-YLMETHYL] ESTER

ChemComp-POP:
PYROPHOSPHATE 2-

ChemComp-IPA:
ISOPROPYL ALCOHOL / alkaloid*YM

ChemComp-HOH:
WATER

ChemComp-IMG:
1,4-DIDEOXY-1,4-IMINO-1-(S)-(9-DEAZAGUANIN-9-YL)-D-RIBITOL

Source
  • giardia intestinalis (eukaryote)
KeywordsTRANSFERASE / protein-inhibitor complex / Mg ions / pyrophosphate / transition state analogue / immucillinG / 9-deazaguanine

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