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TitleCrystal structure of active site-inhibited human coagulation factor VIIa (des-Gla).
Journal, issue, pagesJ. Struct. Biol., Vol. 127, Page 213-223, Year 1999
Publish dateAug 24, 1999 (structure data deposition date)
AuthorsKemball-Cook, G. / Johnson, D.J. / Tuddenham, E.G. / Harlos, K.
External linksJ. Struct. Biol. / PubMed:10544046
MethodsX-ray diffraction
Resolution2.28 Å
Structure data

PDB-1cvw:
Crystal structure of active site-inhibited human coagulation factor VIIA (DES-GLA)
Method: X-RAY DIFFRACTION / Resolution: 2.28 Å

Chemicals

ChemComp-0GE:
N-{[5-(dimethylamino)naphthalen-1-yl]sulfonyl}-L-alpha-glutamyl-N-[(2S,3S)-6-carbamimidamido-1-chloro-2-hydroxyhexan-3-yl]glycinamide

ChemComp-CA:
Unknown entry

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsHYDROLASE/HYDROLASE INHIBITOR / BLOOD COAGULATION / FACTOR VIIA / SERINE PROTEASE / EGF / HYDROLASE-HYDROLASE INHIBITOR complex

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