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Structure paper

TitleDetoxification of environmental mutagens and carcinogens: structure, mechanism, and evolution of liver epoxide hydrolase.
Journal, issue, pagesProc. Natl. Acad. Sci. USA, Vol. 96, Page 10637-10642, Year 1999
Publish dateAug 12, 1999 (structure data deposition date)
AuthorsArgiriadi, M.A. / Morisseau, C. / Hammock, B.D. / Christianson, D.W.
External linksProc. Natl. Acad. Sci. USA / PubMed:10485878
MethodsX-ray diffraction
Resolution2.8 Å
Structure data

PDB-1cqz:
CRYSTAL STRUCTURE OF MURINE SOLUBLE EPOXIDE HYDROLASE.
Method: X-RAY DIFFRACTION / Resolution: 2.8 Å

PDB-1cr6:
CRYSTAL STRUCTURE OF MURINE SOLUBLE EPOXIDE HYDROLASE COMPLEXED WITH CPU INHIBITOR
Method: X-RAY DIFFRACTION / Resolution: 2.8 Å

Chemicals

ChemComp-HOH:
WATER

ChemComp-CPU:
N-CYCLOHEXYL-N'-(PROPYL)PHENYL UREA

Source
  • mus musculus (house mouse)
KeywordsHYDROLASE / HOMODIMER / ALPHA/BETA HYDROLASE FOLD / DOMAIN-SWAPPING / DISUBSTITUTED UREA INHIBITOR

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