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TitleSlow-binding inhibition of Escherichia coli cystathionine beta-lyase by L-aminoethoxyvinylglycine: a kinetic and X-ray study.
Journal, issue, pagesBiochemistry, Vol. 36, Page 12633-12643, Year 1997
Publish dateSep 4, 1997 (structure data deposition date)
AuthorsClausen, T. / Huber, R. / Messerschmidt, A. / Pohlenz, H.D. / Laber, B.
External linksBiochemistry / PubMed:9376370
MethodsX-ray diffraction
Resolution2.2 Å
Structure data

PDB-1cl2:
CYSTATHIONINE BETA-LYASE (CBL) FROM ESCHERICHIA COLI IN COMPLEX WITH AMINOETHOXYVINYLGLYCINE
Method: X-RAY DIFFRACTION / Resolution: 2.2 Å

Chemicals

ChemComp-PPG:
(2E,3E)-4-(2-aminoethoxy)-2-[({3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}methyl)imino]but-3-enoic acid

ChemComp-HOH:
WATER

Source
  • escherichia coli (E. coli)
KeywordsMETHIONINE BIOSYNTHESIS / PLP-DEPENDENT ENZYMES / C-S BETA LYASE / AMINOETHOXYVINYLGLYCINE / SLOW-BINDING INHIBITION

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