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| Title | X-ray structure of human stromelysin catalytic domain complexed with nonpeptide inhibitors: implications for inhibitor selectivity. |
|---|---|
| Journal, issue, pages | Protein Sci., Vol. 8, Page 1455-1462, Year 1999 |
| Publish date | Feb 3, 1999 (structure data deposition date) |
Authors | Pavlovsky, A.G. / Williams, M.G. / Ye, Q.Z. / Ortwine, D.F. / Purchase II, C.F. / White, A.D. / Dhanaraj, V. / Roth, B.D. / Johnson, L.L. / Hupe, D. ...Pavlovsky, A.G. / Williams, M.G. / Ye, Q.Z. / Ortwine, D.F. / Purchase II, C.F. / White, A.D. / Dhanaraj, V. / Roth, B.D. / Johnson, L.L. / Hupe, D. / Humblet, C. / Blundell, T.L. |
External links | PubMed:10422833 |
| Methods | X-ray diffraction |
| Resolution | 1.64 - 2 Å |
| Structure data | ![]() PDB-1b8y: ![]() PDB-1caq: ![]() PDB-1ciz: ![]() PDB-1qia: ![]() PDB-1qic: |
| Chemicals | ![]() ChemComp-ZN: ![]() ChemComp-CA: ![]() ChemComp-SO4: ![]() ChemComp-IN7: ![]() ChemComp-HOH: ![]() ChemComp-DPS: |
| Source |
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Keywords | HYDROLASE / MATRIX METALLOPROTEINASE-3 / STROMELYSIN-1 / MATRIX METALLOPROTEINASE / MMP-3 / NON-PEPTIDE INHIBITOR / METALLOPROTEINASE / INHIBITOR / MATRIXIN / MATRIX METALLOPROTEINASE-3 (MMP-3) / METZINCIN |
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homo sapiens (human)
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