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TitleCrystal structure of a murine glutathione S-transferase in complex with a glutathione conjugate of 4-hydroxynon-2-enal in one subunit and glutathione in the other: evidence of signaling across the dimer interface.
Journal, issue, pagesBiochemistry, Vol. 38, Page 11887-11894, Year 1999
Publish dateJan 6, 1999 (structure data deposition date)
AuthorsXiao, B. / Singh, S.P. / Nanduri, B. / Awasthi, Y.C. / Zimniak, P. / Ji, X.
External linksBiochemistry / PubMed:10508391
MethodsX-ray diffraction
Resolution2.6 Å
Structure data

PDB-1b48:
CRYSTAL STRUCTURE OF MGSTA4-4 IN COMPLEX WITH GSH CONJUGATE OF 4-HYDROXYNONENAL IN ONE SUBUNIT AND GSH IN THE OTHER: EVIDENCE OF SIGNALING ACROSS DIMER INTERFACE IN MGSTA4-4
Method: X-RAY DIFFRACTION / Resolution: 2.6 Å

Chemicals

ChemComp-HAG:
4-S-GLUTATHIONYL-5-PENTYL-TETRAHYDRO-FURAN-2-OL

ChemComp-GSH:
GLUTATHIONE

ChemComp-HOH:
WATER

Source
  • mus musculus (house mouse)
KeywordsTRANSFERASE / GLUTATHIONE S-TRANSFERASE / GST / SUBUNIT COOPERATIVITY

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