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Structure paper

TitleCrystal structure of human type II inosine monophosphate dehydrogenase: implications for ligand binding and drug design.
Journal, issue, pagesProc. Natl. Acad. Sci. USA, Vol. 96, Page 3531-3536, Year 1999
Publish dateDec 14, 1998 (structure data deposition date)
AuthorsColby, T.D. / Vanderveen, K. / Strickler, M.D. / Markham, G.D. / Goldstein, B.M.
External linksProc. Natl. Acad. Sci. USA / PubMed:10097070
MethodsX-ray diffraction
Resolution2.9 Å
Structure data

PDB-1b3o:
TERNARY COMPLEX OF HUMAN TYPE-II INOSINE MONOPHOSPHATE DEHYDROGENASE WITH 6-CL-IMP AND SELENAZOLE ADENINE DINUCLEOTIDE
Method: X-RAY DIFFRACTION / Resolution: 2.9 Å

Chemicals

ChemComp-CPR:
6-CHLOROPURINE RIBOSIDE, 5'-MONOPHOSPHATE

ChemComp-SAE:
SELENAZOLE-4-CARBOXYAMIDE-ADENINE DINUCLEOTIDE

ChemComp-UNX:
Unknown entry

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsDEHYDROGENASE / IMPD / IMPDH / GUANINE NUCLEOTIDE SYNTHESIS

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