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Structure paper

TitleComplexes of adenosine deaminase with two potent inhibitors: X-ray structures in four independent molecules at pH of maximum activity.
Journal, issue, pagesBiochemistry, Vol. 37, Page 8314-8324, Year 1998
Publish dateJan 31, 1998 (structure data deposition date)
AuthorsWang, Z. / Quiocho, F.A.
External linksBiochemistry / PubMed:9622483
MethodsX-ray diffraction
Resolution1.95 - 2.6 Å
Structure data

PDB-1a4l:
ADA STRUCTURE COMPLEXED WITH DEOXYCOFORMYCIN AT PH 7.0
Method: X-RAY DIFFRACTION / Resolution: 2.6 Å

PDB-1a4m:
ADA STRUCTURE COMPLEXED WITH PURINE RIBOSIDE AT PH 7.0
Method: X-RAY DIFFRACTION / Resolution: 1.95 Å

Chemicals

ChemComp-ZN:
Unknown entry

ChemComp-DCF:
2'-DEOXYCOFORMYCIN / anticancer*YM

ChemComp-HOH:
WATER

ChemComp-PRH:
6-HYDROXY-1,6-DIHYDRO PURINE NUCLEOSIDE

Source
  • mus musculus (house mouse)
KeywordsHYDROLASE / ADENOSINE DEAMINASE / PENTOSTATIN / DEOXYCOFORMYCIN / PURINE RIBOSIDE

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