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Structure paper

TitleType IV-C CRISPR-Cas effector complex recognizes double-stranded DNA and switches on collateral cleavage of ssDNA and RNA
Journal, issue, pagesTo Be Published
Publish dateFeb 21, 2026 (structure data deposition date)
AuthorsPittman C / Xu C / Catchpole R / Garrett S / Fuchs R / Makarova K / Koonin E / Zhao P / Wells L / Graveley B ...Pittman C / Xu C / Catchpole R / Garrett S / Fuchs R / Makarova K / Koonin E / Zhao P / Wells L / Graveley B / Chu X / Ke A / Terns M
External linksSearch PubMed
MethodsEM (single particle)
Resolution3.2 - 3.37 Å
Structure data

75667

11fs

EMDB-75667, PDB-11fs:
Effector complex from type IV-C CRISPR-Cas system
Method: EM (single particle) / Resolution: 3.2 Å

75685

11hc

EMDB-75685, PDB-11hc:
Effector complex from type IV-C CRISPR-Cas system
Method: EM (single particle) / Resolution: 3.37 Å

75686

11hd

EMDB-75686, PDB-11hd:
Effector complex from type IV-C CRISPR-Cas system
Method: EM (single particle) / Resolution: 3.21 Å

Chemicals

ChemComp-MG:
Unknown entry

ChemComp-ZN:
Unknown entry

Source
  • pyrococcus abyssi (archaea)
KeywordsRNA BINDING PROTEIN / CRISPR-Cas / nuclease / RNA-guided / Cas10 / Cas7

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