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-Structure paper
| Title | Conformational cycling of the Wntless transporter drives trafficking and secretion of Wnt morphogens |
|---|---|
| Journal, issue, pages | To Be Published |
| Publish date | Nov 10, 2025 (structure data deposition date) |
Authors | Ge Y / de Almeida Magalhaes T / Wu H / van den Boomen DJH / Nguyen TU / Dou T / Yadav GP / Lee S / Wang Z / Lemoff A ...Ge Y / de Almeida Magalhaes T / Wu H / van den Boomen DJH / Nguyen TU / Dou T / Yadav GP / Lee S / Wang Z / Lemoff A / Luo X / Jin Z / Jiang J / Salic A / Huang P |
External links | Search PubMed |
| Methods | EM (single particle) |
| Resolution | 2.63 - 3.38 Å |
| Structure data | EMDB-73803, PDB-9z4h: EMDB-73810, PDB-9z4o: ![]() EMDB-73835: Cryo-EM structure of human Wntless-Wnt5a 2:2 complex - Focused map A ![]() EMDB-73836: Cryo-EM structure of human Wntless-Wnt5a 2:2 complex - Focused map B ![]() EMDB-73837: Cryo-EM structure of human Wntless-Wnt5a 2:2 complex - Consensus map EMDB-73838, PDB-9z67: |
| Chemicals | ![]() ChemComp-PAM: ![]() ChemComp-NAG: ![]() ChemComp-PCW: ![]() ChemComp-CLR: ![]() ChemComp-LPE: |
| Source |
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Keywords | MEMBRANE PROTEIN / Wnt transporter / Wnt5a / Wnt signaling / Wnt secretion |
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homo sapiens (human)
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