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TitleHIV-1 CA hexamer from purified viral cores bound to lenacapavir, C6 symmetry
Journal, issue, pagesTo Be Published
Publish dateSep 10, 2025 (structure data deposition date)
AuthorsBarros dos Santos NF / Ganser-Pornillos BK / Pornillos O
External linksSearch PubMed
MethodsEM (single particle)
Resolution2.83 Å
Structure data

72657

9y7j

EMDB-72657, PDB-9y7j:
HIV-1 CA hexamer from purified viral cores bound to lenacapavir, C6 symmetry
Method: EM (single particle) / Resolution: 2.83 Å

Chemicals

ChemComp-QNG:
N-[(1S)-1-(3-{4-chloro-3-[(methylsulfonyl)amino]-1-(2,2,2-trifluoroethyl)-1H-indazol-7-yl}-6-[3-methyl-3-(methylsulfonyl)but-1-yn-1-yl]pyridin-2-yl)-2-(3,5-difluorophenyl)ethyl]-2-[(3bS,4aR)-5,5-difluoro-3-(trifluoromethyl)-3b,4,4a,5-tetrahydro-1H-cyclopropa[3,4]cyclopenta[1,2-c]pyrazol-1-yl]acetamide / medication, antiretroviral*YM

Source
  • human immunodeficiency virus 1
KeywordsVIRAL PROTEIN / capsid / native purified HIV cores

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