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TitleCryo-EM structure of the DCAF11 E3 ligase bound to the DDX18 helicase mediated by GSH-M12
Journal, issue, pagesTo Be Published
Publish dateJul 27, 2025 (structure data deposition date)
AuthorsWachter F / Jin CY / Yoon H / Ebert BL / Fischer ES
External linksSearch PubMed
MethodsEM (single particle)
Resolution2.35 - 2.38 Å
Structure data

EMDB-71833: Cryo-EM structure of the DCAF11 E3 ligase bound to the DDX18 helicase mediated by GSH-M12 (DDX18 local refinement)
Method: EM (single particle) / Resolution: 2.38 Å

EMDB-71834: Cryo-EM structure of the DCAF11 E3 ligase bound to the DDX18 helicase mediated by GSH-M12 (consensus refinement)
Method: EM (single particle) / Resolution: 2.35 Å

71847

9ptu

EMDB-71847, PDB-9ptu:
Cryo-EM structure of the DCAF11 E3 ligase bound to the DDX18 helicase mediated by GSH-M12
Method: EM (single particle) / Resolution: 2.38 Å

Chemicals


PDB Unreleased entry

PDB-1ck5: Unknown entry

Source
  • homo sapiens (human)
KeywordsLIGASE / glutathionylation / degradation / E3 ligase / helicase

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