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TitleStructural characterization of the HDV virion and its ribonucleoprotein
Journal, issue, pagesProc. Natl. Acad. Sci. USA, Vol. 123, Year 2026
Publish dateJul 23, 2025 (structure data deposition date)
AuthorsItskanov S / Ary B / Mehra U / Lew I / Novikov N / Schmitz U / Holdorf MM / Beran RK / Lansdon EB
External linksProc. Natl. Acad. Sci. USA / Search PubMed
MethodsEM (subtomogram averaging) / EM (single particle)
Resolution3.5 - 36.0 Å
Structure data

EMDB-71803: HDV particle subtomogram reconstruction
Method: EM (subtomogram averaging) / Resolution: 36.0 Å

EMDB-71804: Linear arrangement of the HDV 311-RNP
Method: EM (single particle) / Resolution: 7.3 Å

EMDB-71805: Twisted arrangement of the HDV 311-RNP
Method: EM (single particle) / Resolution: 7.29 Å

EMDB-71806: Twisted arrangement of the HDV 311-RNP, Multibody refinement, Body 1
Method: EM (single particle) / Resolution: 7.3 Å

71807

9prc

EMDB-71807, PDB-9prc:
HDAg complex with 86-pRNA, Body1
Method: EM (single particle) / Resolution: 3.5 Å

EMDB-71808: HDAg complex with 86-pRNA, Body2
Method: EM (single particle) / Resolution: 3.5 Å

Source
  • hepatitis delta virus
  • synthetic construct (others)
KeywordsVIRUS / HDV / HDAg / RNP / RNA

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