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TitleBacterial 2',3'-cGAMP activates a SAVED effector to form membrane-disrupting filaments and restrict phage replication
Journal, issue, pagesTo Be Published
Publish dateMay 13, 2025 (structure data deposition date)
AuthorsTak U / Schinkel K / Walth P / Tay JW / Hartwick EW / Whiteley AT
External linksSearch PubMed
MethodsEM (single particle)
Resolution3.3 Å
Structure data

70609

9om7

EMDB-70609, PDB-9om7:
BtCap14 SAVED domain + 2',3'-cGAMP
Method: EM (single particle) / Resolution: 3.3 Å

Chemicals

ChemComp-1SY:
cGAMP

Source
  • bacillus thuringiensis (bacteria)
KeywordsANTIVIRAL PROTEIN / Saf-2TM-SAVED / Cap14 / cGAMP / antiphage

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