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TitleCryo-EM Structures of the Human Astrovirus VA1 Capsid Spike Bound to Neutralizing Antibodies: Implications for Therapeutic Strategies
Journal, issue, pagesTo Be Published
Publish dateApr 28, 2025 (structure data deposition date)
AuthorsGhosh A / Dzimianski JV / Lopez T / Espinosa R / Balasco Serrao VH / Arias CF / DuBois RM
External linksSearch PubMed
MethodsEM (single particle)
Resolution2.69 - 3.05 Å
Structure data

70397
EMDB Unreleased entry

9oef

EMDB-70397, PDB-9oef:
Structure of the human astrovirus VA1 capsid spike bound to antibody 7C8
Method: EM (single particle) / Resolution: 2.69 Å

70398
EMDB Unreleased entry

9oeg

EMDB-70398, PDB-9oeg:
Structure of the human astrovirus VA1 capsid spike bound to antibody 2A2
Method: EM (single particle) / Resolution: 3.05 Å

Source
  • astrovirus va1
  • mus musculus (house mouse)
KeywordsVIRAL PROTEIN / Astrovirus / neutralizing antibody / epitope mapping / neurovirulent.

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