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Structure paper

TitleStructural principles underlying the evolution of SWI/SNF chromatin remodelers
Journal, issue, pagesSci Adv, Year 2026
Publish dateFeb 1, 2026 (structure data deposition date)
AuthorsMa SS / Liu MD / Xu WC / Wang QM / Wang XM / Huang YG / Li MC / Li CH / Shen QT / Chen Y
External linksSearch PubMed
MethodsEM (single particle)
Resolution2.96 - 4.84 Å
Structure data

68865

23cp

EMDB-68865, PDB-23cp:
Cryo-EM structure of RSC complex from Chaetomium thermophilum
Method: EM (single particle) / Resolution: 3.12 Å

68925

23fj

EMDB-68925, PDB-23fj:
Cryo-EM structure of SWI/SNF complex from Chaetomium thermophilum
Method: EM (single particle) / Resolution: 2.96 Å

EMDB-68926: The focused refined map for ATPase-ARP-NCP region from the Chaetomium thermophilum RSC-NCP complex
Method: EM (single particle) / Resolution: 4.06 Å

EMDB-68927: The consensus map for the complete Chaetomium thermophilum RSC-NCP complex
Method: EM (single particle) / Resolution: 4.45 Å

EMDB-68928: The focused refined map for the base module from the Chaetomium thermophilum RSC-NCP complex
Method: EM (single particle) / Resolution: 3.78 Å

68935

23fu

EMDB-68935, PDB-23fu:
Cryo-EM structure of Chaetomium thermophilum RSC bound to a nucleosome
Method: EM (single particle) / Resolution: 4.45 Å

EMDB-68940: The consensus map for the complete Chaetomium thermophilum SWI/SNF-NCP complex
Method: EM (single particle) / Resolution: 3.46 Å

EMDB-68942: The focused refined map for the base module from the Chaetomium thermophilum SWI/SNF-NCP complex
Method: EM (single particle) / Resolution: 3.4 Å

EMDB-68952: The focused refined map for the ATPase-ARP module from the Chaetomium thermophilum SWI/SNF-NCP complex
Method: EM (single particle) / Resolution: 4.84 Å

EMDB-68953: The focused refined map for the nucleosome region from the Chaetomium thermophilum SWI/SNF-NCP complex
Method: EM (single particle) / Resolution: 3.09 Å

68999

23il

EMDB-68999, PDB-23il:
Cryo-EM structure of Chaetomium thermophilum SWI/SNF bound to a nucleosome
Method: EM (single particle) / Resolution: 3.46 Å

EMDB-69438: The consensus map for the Chaetomium thermophilum RSC complex in the free state
Method: EM (single particle) / Resolution: 3.12 Å

EMDB-69475: The focused refined map for RSC-specific lobe of the Chaetomium thermophilum RSC complex
Method: EM (single particle) / Resolution: 4.72 Å

Chemicals

ChemComp-ZN:
Unknown entry

ChemComp-ADP:
ADENOSINE-5'-DIPHOSPHATE / ADP, energy-carrying molecule*YM

Source
  • thermochaetoides thermophila dsm 1495 (fungus)
  • Thermochaetoides thermophila (fungus)
  • xenopus laevis (African clawed frog)
  • synthetic construct (others)
KeywordsDNA BINDING PROTEIN / SWI/SNF-family chromatin remodeling / RSC / PBAF / NUCLEAR PROTEIN / Chromatin remodeling complex / SWI/SNF / nucleosome / NUCLEAR PROTEIN/DNA / NUCLEAR PROTEIN-DNA complex

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