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-Structure paper
| タイトル | A C-based single-domain antibody broadly neutralizes SARS-CoV-2 and its variants through novel recognition of conserved regions in RBD |
|---|---|
| ジャーナル・号・ページ | To Be Published |
| 掲載日 | 2024年5月15日 (構造データの登録日) |
著者 | Wu B / Rao G / Zhang H / Yi Y / Zhao S / Qin Y / Li M / Chen L / Zhang Z / Mu J ...Wu B / Rao G / Zhang H / Yi Y / Zhao S / Qin Y / Li M / Chen L / Zhang Z / Mu J / Chiu S / Cao S / Gong R |
リンク | PubMedで検索 |
| 手法 | EM (単粒子) |
| 解像度 | 2.51 - 4.22 Å |
| 構造データ | ![]() EMDB-60186: spike glycoprotein of SARS-CoV2 EG.5 ![]() EMDB-60187: Spike glycoprotein of SARS-CoV2 EG.5.1 ![]() EMDB-60188: Spike glycoprotein of SARS-CoV2 BA.1 ![]() EMDB-64592: The binding of a C-based single-domain antibody stabilizes spikes of SARS-CoV2 (JN.1) in all-RBD-up conformation ![]() EMDB-64593: The binding of a C-based single-domain antibody stabilizes spikes of SARS-CoV2 (Delta) in all-RBD-up conformation ![]() EMDB-64594: The binding of a C-based single-domain antibody stabilizes spikes of SARS-CoV2 (BA.5) in all-RBD-up conformation ![]() EMDB-64595: The binding of a C-based single-domain antibody stabilizes spikes of SARS-CoV2 (BA.2) in all-RBD-up conformation ![]() EMDB-64596: The binding of a C-based single-domain antibody stabilizes spikes of SARS-CoV2 (BA.1) in all-RBD-up conformation EMDB-64597, PDB-9uxs: ![]() EMDB-64598: Three RBD domains of the spike protein of SARS-CoV-2 JN.1 present all down conformation. ![]() EMDB-64599: Three RBD domains of the spike protein of SARS-CoV-2 JN.1 present two up and one down conformation ![]() EMDB-64600: Three RBD domains of the spike protein of SARS-CoV-2 JN.1 present one up and two down conformation |
| 由来 |
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キーワード | VIRAL PROTEIN/IMMUNE SYSTEM / SARS-CoV2 / RBD / Single-domain antibody / VIRAL PROTEIN-IMMUNE SYSTEM complex |
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