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-Structure paper
| Title | Structure-based engineering of the midnolin-proteasome pathway for targeted protein degradation. |
|---|---|
| Journal, issue, pages | Protein Cell, Vol. 17, Issue 1, Page 83-88, Year 2026 |
| Publish date | Jan 1, 2026 |
Authors | Hongyang Wang / Ying Zheng / Tiantian Wang / Xue Zhang / Peipei Wang / Chuancun Wei / Hongyue Li / Quan Wang / Lu Zhang / Xisong Ke / Wenqing Xu / ![]() |
External links | Protein Cell / PubMed:40851512 / PubMed Central |
| Methods | EM (single particle) |
| Resolution | 3.31 - 4.32 Å |
| Structure data | EMDB-63592, PDB-9m2w: EMDB-64103, PDB-9uf8: EMDB-64133, PDB-9ug9: ![]() EMDB-65264: The composite map of midnolin and 26S proteasome complex with Catch domain in MB state |
| Chemicals | ![]() ChemComp-ATP: ![]() ChemComp-ADP: ![]() ChemComp-ZN: |
| Source |
|
Keywords | HYDROLASE / midnolin / 26S proteasome / complex / MD state |
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homo sapiens (human)
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