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Structure paper

TitleStructural and biochemical basis for the pathogenic mutations of methylmalonate semialdehyde dehydrogenase ALDH6A1
Journal, issue, pagesMedicine Plus, Vol. 1, Page 100056, Year 2024
Publish dateAug 1, 2024 (structure data deposition date)
AuthorsSu G / Ju K / Xu Y / Jin Y / Chen L / Luan X
External linksMedicine Plus / Search PubMed
MethodsEM (single particle)
Resolution3.0 - 3.7 Å
Structure data

61042

9izu

EMDB-61042, PDB-9izu:
Cryo-EM structure of ALDH6A1-P62S
Method: EM (single particle) / Resolution: 3.7 Å

61043

9izv

EMDB-61043, PDB-9izv:
Cryo-EM structure of ALDH6A1-Y172H & R535C
Method: EM (single particle) / Resolution: 3.02 Å

61044

9izw

EMDB-61044, PDB-9izw:
Cryo-EM structure of ALDH6A1-S262Y
Method: EM (single particle) / Resolution: 3.12 Å

61045

9izx

EMDB-61045, PDB-9izx:
Cryo-EM structure of ALDH6A1-G446R
Method: EM (single particle) / Resolution: 3.0 Å

Source
  • homo sapiens (human)
KeywordsHYDROLASE / ALDH6A1 / P62S / Y172H / R535C / S262Y / G446R

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