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Structure paper

TitleNAC promotes co-translational protein folding at the ribosomal tunnel exit
Journal, issue, pagesMol. Cell, Year 2026
Publish dateFeb 5, 2026 (structure data deposition date)
AuthorsSantos J / Gunnigmann M / Gora RJ / Iljina M / Predin M / Kotan IE / De P / Choudhary D / Jang J / Tippmann F ...Santos J / Gunnigmann M / Gora RJ / Iljina M / Predin M / Kotan IE / De P / Choudhary D / Jang J / Tippmann F / Hins C / Ban N / Tans SJ / Shan SO / Kramer G / Bukau B
External linksMol. Cell / Search PubMed
MethodsEM (single particle)
Resolution3.3 - 3.5 Å
Structure data

EMDB-56582: XBP1u-stalled RPL4 RNC in complex with NAC (locally refined on 40S body)
Method: EM (single particle) / Resolution: 3.5 Å

EMDB-56583: XBP1u-stalled RPL4 RNC in complex with NAC (locally refined on 40S head)
Method: EM (single particle) / Resolution: 3.3 Å

Source
  • Homo sapiens (human)

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