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Structure paper

TitleA Carboxylate Switch Point Controls Long-Range Energy Transduction in Respiratory Complex I
Journal, issue, pagesTo Be Published
Publish dateNov 18, 2025 (structure data deposition date)
AuthorsBeghiah A / Saura P / Kovalova T / Hoeser F / Friedrich T / Kaila VRI
External linksSearch PubMed
MethodsEM (single particle)
Resolution2.59 - 3.0 Å
Structure data

55748

9taj

EMDB-55748, PDB-9taj:
E. coli Complex I WT purified in LMNG
Method: EM (single particle) / Resolution: 3.0 Å

55749

9tak

EMDB-55749, PDB-9tak:
Local refinement of E. coli Complex I WT membrane domain in LMNG
Method: EM (single particle) / Resolution: 2.8 Å

55750

9tal

EMDB-55750, PDB-9tal:
Local refinement of E. coli Complex I WT hydrophilic domain in LMNG
Method: EM (single particle) / Resolution: 2.66 Å

55751

9tam

EMDB-55751, PDB-9tam:
E. coli Complex I D79N NuoA mutant purified in LMNG
Method: EM (single particle) / Resolution: 2.96 Å

55752

9tan

EMDB-55752, PDB-9tan:
Local refinement of E. coli Complex I D79N NuoA mutant hydrophilic domain in LMNG
Method: EM (single particle) / Resolution: 2.59 Å

55753

9tao

EMDB-55753, PDB-9tao:
Local refinement of E. coli Complex I D79N NuoA mutant membrane domain in LMNG
Method: EM (single particle) / Resolution: 2.61 Å

Chemicals

ChemComp-FES:
FE2/S2 (INORGANIC) CLUSTER

ChemComp-CA:
Unknown entry

ChemComp-FMN:
FLAVIN MONONUCLEOTIDE

ChemComp-SF4:
IRON/SULFUR CLUSTER

ChemComp-3PE:
1,2-Distearoyl-sn-glycerophosphoethanolamine / phospholipid*YM

ChemComp-LFA:
EICOSANE

ChemComp-CDL:
CARDIOLIPIN / phospholipid*YM

ChemComp-TRD:
TRIDECANE

ChemComp-UQ8:
Ubiquinone-8

ChemComp-HOH:
WATER

ChemComp-7PH:
(1R)-2-(dodecanoyloxy)-1-[(phosphonooxy)methyl]ethyl tetradecanoate

Source
  • escherichia coli bw25113 (bacteria)
  • escherichia coli bl21(de3) (bacteria)
KeywordsPROTON TRANSPORT / bioenergetics / Leigh's syndrome

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