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| Title | Substrate-induced assembly and functional mechanism of the membrane protein insertase SecYEG-YidC. |
|---|---|
| Journal, issue, pages | Embo J., Year 2026 |
| Publish date | Nov 6, 2025 |
Authors | Busch, M. / Rosales-Hernandez, C. / Kamel, M. / Schaumkessel, Y. / van der Sluis, E.O. / Berninghausen, O. / Becker, T. / Beckmann, R. / Kedrov, A. |
External links | Embo J. / PubMed:42362696 |
| Methods | EM (single particle) |
| Resolution | 2.44 - 3.76 Å |
| Structure data | ![]() EMDB-53560: Structure of a stalled E. coli 70S RNC-NuoK-48 in complex with the SecYEG Translocon. ![]() EMDB-53568: Structure of a stalled E. coli 70S RNC-NuoK-48 in complex with the SecYEG Translocon (Focused Refinement) ![]() EMDB-53584: Structure of a stalled E. coli 70S RNC-NuoK-86-E36K-E76K-mutant in complex with the SecYEG-YidC membrane protein insertase ![]() EMDB-53585: Structure of a stalled E. coli 70S RNC-NuoK-86-E36K-E76K-mutant in complex with the SecYEG-YidC membrane protein insertase (Focused Refinement) ![]() EMDB-53587: Structure of a stalled E. coli 70S RNC-NuoK-86 in complex with the SecYEG-YidC membrane protein insertase ![]() EMDB-53589: Structure of a stalled E. coli 70S RNC-NuoK-86 in complex with the SecYEG-YidC membrane protein insertase (Focused Refinement) EMDB-53892, PDB-9rbf: ![]() EMDB-53893: Structure of a stalled E. coli 70S RNC-NuoK-86 in complex with the membrane protein insertase SecYEG-YidC (Focused Refinement) ![]() EMDB-53894: Structure of a stalled E. coli 70S RNC-NuoK-86 in complex with the membrane protein insertase SecYEG-YidC (Composite map) ![]()
EMDB-55568: Structure of a stalled E. coli 70S RNC-NuoK-86 in complex with SecYEG (Consensus Refinement) ![]()
EMDB-55570: Structure of a stalled E. coli 70S RNC-NuoK-70 in complex with SecYEG-YidC (Consensus Refinement) ![]()
EMDB-55571: Structure of a stalled E. coli 70S RNC-NuoK-70 in complex with SecYEG-YidC (Focused Refinement) EMDB-55598, PDB-9t5x: |
| Chemicals | ![]() ChemComp-ZN: ![]() ChemComp-MG: ![]() ChemComp-PRO: ![]() ChemComp-SPM: ![]() ChemComp-PRI: |
| Source |
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Keywords | PROTEIN TRANSPORT / 70S Ribosome / SecYEG translocon / YidC / NuoK |
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