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Structure paper

TitleStructural basis of TACO1 function in human mitochondrial translation
Journal, issue, pagesTo Be Published
Publish dateJul 3, 2025 (structure data deposition date)
AuthorsSingh V / Whitford PC / Khawaja A / Rorbach J
External linksSearch PubMed
MethodsEM (single particle)
Resolution2.64 Å
Structure data

54264

9ru6

EMDB-54264, PDB-9ru6:
Human mitoribosome bound to TACO1 (Translational activator of COX1), mRNA, A/A-, P/P- and (partial) E/E-tRNAs
Method: EM (single particle) / Resolution: 2.64 Å

Chemicals

ChemComp-NAD:
NICOTINAMIDE-ADENINE-DINUCLEOTIDE / NAD*YM

ChemComp-MG:
Unknown entry

ChemComp-K:
Unknown entry

ChemComp-5F0:
(3~{S})-3-azanyl-4-methoxy-4-oxidanylidene-butanoic acid

ChemComp-ZN:
Unknown entry

ChemComp-FES:
FE2/S2 (INORGANIC) CLUSTER

ChemComp-ATP:
ADENOSINE-5'-TRIPHOSPHATE / ATP, energy-carrying molecule*YM

ChemComp-GDP:
GUANOSINE-5'-DIPHOSPHATE / GDP, energy-carrying molecule*YM

ChemComp-SPD:
SPERMIDINE

ChemComp-VOL:
L-VALINOL

Source
  • homo sapiens (human)
KeywordsRIBOSOME / mitochondria / mitoribosome / translation activator of COX1

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