EMDB/PDB/SASBDBから引用されている文献のデータベース

キーワード
構造解析手法	All X線回折 NMR 電子顕微鏡小角散乱中性子線回折線維回折粉末回折赤外分光 EPR FRET 理論モデルハイブリッド
著者・登録者
ジャーナル
IF	>30 >20 >10 >5 all

タイトル	Insights into the structure and initial host attachment of the flagellotropic bacteriophage 7-7-1.
ジャーナル・号・ページ	Commun Biol, Vol. 9, Issue 1, Page 55, Year 2025
掲載日	2025年12月6日
著者	W E M Noteborn / R Ouyang / T Hoeksma / A Sidi Mabrouk / N C Esteves / D M Pelt / B E Scharf / A Briegel /
PubMed 要旨	Understanding the structural and functional mechanisms of bacteriophage 7-7-1, the flagellotropic phage infecting Agrobacterium sp. H13-3, offers promising insights into phage-host interactions. ...Understanding the structural and functional mechanisms of bacteriophage 7-7-1, the flagellotropic phage infecting Agrobacterium sp. H13-3, offers promising insights into phage-host interactions. Using single particle analysis (SPA) cryo-electron microscopy (cryo-EM), we determined the capsid, neck region, tail, and baseplate complex structures. Combined with cryo-electron tomography (cryo-ET) and machine learning methodologies, our findings indicate that phage 7-7-1 uses capsid fibers to establish initial contact with the host flagellum, followed by subsequent attachment to cell surface receptors. The study also demonstrated that capsid fibers are flexible and can interact with other phages and host flagella, suggesting a cooperative infection strategy. These results provide crucial structural insights and may open avenues for developing phage-based therapeutics against resistant bacterial pathogens.
リンク	Commun Biol / PubMed:41353512 / PubMed Central
手法	EM (単粒子) / EM (トモグラフィー)
解像度	3.03 - 3.56 Å
構造データ	52521 9hz7 EMDB-52521, PDB-9hz7: Agrobacterium phage 7-7-1 tail 手法: EM (単粒子) / 解像度: 3.03 Å 52522 9hz8 EMDB-52522, PDB-9hz8: Agrobacterium phage 7-7-1 capsid 手法: EM (単粒子) / 解像度: 3.4 Å EMDB-53352: Cryo-tomogram of Agrobacterium phage 7-7-1 and Agrobacterium sp. H13-3 手法: EM (トモグラフィー) 54017 9rkq EMDB-54017, PDB-9rkq: Agrobacterium phage 7-7-1 portal 手法: EM (単粒子) / 解像度: 3.21 Å 54018 9rkr EMDB-54018, PDB-9rkr: Agrobacterium phage 7-7-1 neck 1 手法: EM (単粒子) / 解像度: 3.53 Å 54019 9rks EMDB-54019, PDB-9rks: Agrobacterium phage 7-7-1 neck 2 + tail terminator + tail sheath + tail tube 手法: EM (単粒子) / 解像度: 3.56 Å 54020 9rkt EMDB-54020, PDB-9rkt: Agrobacterium phage 7-7-1 collar 手法: EM (単粒子) / 解像度: 3.31 Å 54021 9rku EMDB-54021, PDB-9rku: Agrobacterium phage 7-7-1 baseplate 手法: EM (単粒子) / 解像度: 3.44 Å 54022 9rkv EMDB-54022: Agrobacterium phage 7-7-1 tail spike PDB-9rkv: Agrobacterium phage 7-7-1 tail fibers 手法: EM (単粒子) / 解像度: 3.52 Å
由来	agrobacterium phage 7-7-1 (ファージ)
キーワード	VIRUS / Flagella phage / Agrobacterium sp. H13-3 / Tail / VIRAL PROTEIN / Capsid / Tail spike / Neck 1 / neck 2 + tail terminator + sheath + tail / Collar / Baseplate