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Structure paper

TitleComplex I from Ovis aries in presence of D1 inhibitor
Journal, issue, pagesTo Be Published
Publish dateMar 7, 2025 (structure data deposition date)
AuthorsSazanov L / Petrova O
External linksSearch PubMed
MethodsEM (single particle)
Resolution3.04 - 3.25 Å
Structure data

EMDB-53045: Membrane domain of Complex I from Ovis aries in presence of D1 inhibitor, Closed state
Method: EM (single particle) / Resolution: 3.24 Å

EMDB-53047: Peripheral arm of Complex I from Ovis aries in presence of D1 inhibitor, Closed state
Method: EM (single particle) / Resolution: 3.25 Å

EMDB-53050: Consensus map of Complex I Ovis aries in presence of D1 inhibitor, Closed state
Method: EM (single particle) / Resolution: 3.25 Å

EMDB-53051: Focused map of Complex I junction from Ovis aries in presence of D1 inhibitor, Closed state
Method: EM (single particle) / Resolution: 3.19 Å

EMDB-53468: Consensus map of Complex I Ovis aries in presence of D1 inhibitor, Open state
Method: EM (single particle) / Resolution: 3.2 Å

EMDB-53469: Membrane domain of Complex I from Ovis aries in presence of D1 inhibitor, Open state
Method: EM (single particle) / Resolution: 3.2 Å

EMDB-53470: Peripheral arm of Complex I from Ovis aries in presence of D1 inhibitor, Open state
Method: EM (single particle) / Resolution: 3.04 Å

53476

9r01

EMDB-53476, PDB-9r01:
Complex I from Ovis aries in presence of D1 inhibitor, Closed state
Method: EM (single particle) / Resolution: 3.25 Å

53477

9r03

EMDB-53477, PDB-9r03:
Complex I from Ovis aries in presence of D1 inhibitor, Open state
Method: EM (single particle) / Resolution: 3.2 Å

Chemicals

ChemComp-3PE:
1,2-Distearoyl-sn-glycerophosphoethanolamine / phospholipid*YM

ChemComp-PC1:
1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE / phospholipid*YM

ChemComp-DGT:
2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE

ChemComp-MG:
Unknown entry

ChemComp-MYR:
MYRISTIC ACID

ChemComp-ZMP:
S-[2-({N-[(2S)-2-hydroxy-3,3-dimethyl-4-(phosphonooxy)butanoyl]-beta-alanyl}amino)ethyl] tetradecanethioate

ChemComp-SF4:
IRON/SULFUR CLUSTER

ChemComp-FMN:
FLAVIN MONONUCLEOTIDE

ChemComp-NAI:
1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE

ChemComp-FES:
FE2/S2 (INORGANIC) CLUSTER

ChemComp-K:
Unknown entry

PDB-1jbt:
CRYSTAL STRUCTURE OF RIBOTOXIN RESTRICTOCIN COMPLEXED WITH A 29-MER SARCIN/RICIN DOMAIN RNA ANALOG

ChemComp-ZN:
Unknown entry

ChemComp-NDP:
NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE

Source
  • ovis aries (sheep)
KeywordsPROTON TRANSPORT / Complex I / inhibitor / respiration / proton pump / NADH:ubiquinone oxidoreductase / membrane protein / mitochondria

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