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-Structure paper
| Title | The Distinct Pharmacological Profile of Emraclidine, a Selective Positive Allosteric Modulator of the M4 Muscarinic Acetylcholine Receptor |
|---|---|
| Journal, issue, pages | To Be Published |
| Publish date | Jan 16, 2025 (structure data deposition date) |
Authors | Pin S / Wonsey-Quinn A / Trabuco M / Toh MF / Te L / Klein E / Catipay G / Smith DL / Gupta K / Hatch J ...Pin S / Wonsey-Quinn A / Trabuco M / Toh MF / Te L / Klein E / Catipay G / Smith DL / Gupta K / Hatch J / Nguyen H / Iredale P |
External links | Search PubMed |
| Methods | EM (single particle) |
| Resolution | 3.1 Å |
| Structure data | ![]() EMDB-52566: Local Refinement of human M4 muscarinic acetylcholine receptor G protein complex bound to selective PAM Emraclidine |
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Homo sapiens (human)