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Structure paper

TitleLocked and loaded: mechanisms of CasDinG recruitment to the type IV-A1 CRISPR effector complex
Journal, issue, pagesTo Be Published
Publish dateFeb 1, 2025 (structure data deposition date)
AuthorsKiernan KA / Taylor DW
External linksSearch PubMed
MethodsEM (single particle)
Resolution3.0 - 3.67 Å
Structure data

EMDB-48858: Type IV-A1 CRISPR effector complex in loaded state, consensus map
Method: EM (single particle) / Resolution: 3.0 Å

EMDB-48859: Type IV-A1 CasDinG loaded state, focused map
Method: EM (single particle) / Resolution: 3.67 Å

48860

9n3y

EMDB-48860, PDB-9n3y:
Type IV-A1 CRISPR effector complex bound to dsDNA and CasDinG - loaded state
Method: EM (single particle) / Resolution: 3.0 Å

EMDB-48861: Type IV-A1 CRISPR effector complex in locked state, consensus map
Method: EM (single particle) / Resolution: 3.04 Å

EMDB-48862: Type IV-A1 CasDinG locked state, focused map
Method: EM (single particle) / Resolution: 3.58 Å

48863

9n3z

EMDB-48863, PDB-9n3z:
Type IV-A1 CRISPR effector complex bound to dsDNA and CasDinG - locked state
Method: EM (single particle) / Resolution: 3.04 Å

Chemicals

ChemComp-ZN:
Unknown entry

Source
  • pseudomonas aeruginosa (bacteria)
  • synthetic construct (others)
KeywordsDNA BINDING PROTEIN / CRISPR / transcriptional regulation / helicase

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