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Structure paper

TitleCryo-EM structures and biochemical assays demonstrate dengue viruses utilize heparin and glycan binding receptor DC-SIGN for infection
Journal, issue, pagesTo Be Published
Publish dateJan 15, 2025 (structure data deposition date)
AuthorsAre VN / Kuhn RJ
External linksSearch PubMed
MethodsEM (single particle)
Resolution3.4 - 6.13 Å
Structure data

48664

9mvc

EMDB-48664, PDB-9mvc:
DENV3 mature structure at 4 degree Celsius
Method: EM (single particle) / Resolution: 3.59 Å

48665

9mvd

EMDB-48665, PDB-9mvd:
Dengue virus serotype-3 (DENV3) immature structure at 4C
Method: EM (single particle) / Resolution: 6.13 Å

48666

9mve

EMDB-48666, PDB-9mve:
Dengue virus serotype-3 (DENV3) complex with DC-SIGN CRD at 4C
Method: EM (single particle) / Resolution: 3.4 Å

48667

9mvf

EMDB-48667, PDB-9mvf:
Dengue virus serotype-4 (DENV4) complex with DCSIGN CRD at 4C
Method: EM (single particle) / Resolution: 3.73 Å

Chemicals

ChemComp-NAG:
2-acetamido-2-deoxy-beta-D-glucopyranose

ChemComp-CA:
Unknown entry

Source
  • dengue virus type 3
  • homo sapiens (human)
  • dengue virus 4 dominica/814669/1981
KeywordsVIRUS / Dengue virus serotype-3 / Structural Genomics / Center for Structural Biology of Infectious Diseases / CSBID / DENV3 / Immature virus / DC-SIGN CRD / DENV4 / DCSIGN

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