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Structure paper

TitleStructural Insights into the Inhibition Mechanism of Human DRA
Journal, issue, pagesTo Be Published
Publish dateMar 20, 2024 (structure data deposition date)
AuthorsFeng JR / Dang S
External linksSearch PubMed
MethodsEM (single particle)
Resolution3.18 - 3.79 Å
Structure data

39538

8yr9

EMDB-39538, PDB-8yr9:
the Cyro-EM Structure of human SLC26A3
Method: EM (single particle) / Resolution: 3.18 Å

39539

8yra

EMDB-39539, PDB-8yra:
The Cyro-EM Structure of human SLC26A3 with specific inhibitor DRAinh-A250
Method: EM (single particle) / Resolution: 3.78 Å

39563

8ys8

EMDB-39563, PDB-8ys8:
The Cyro-EM Structure of human SLC26A3 with non-specific inhibitor Tenidap
Method: EM (single particle) / Resolution: 3.79 Å

Chemicals

ChemComp-Y01:
CHOLESTEROL HEMISUCCINATE

ChemComp-CLR:
CHOLESTEROL

PDB-1lzr:
STRUCTURAL CHANGES OF THE ACTIVE SITE CLEFT AND DIFFERENT SACCHARIDE BINDING MODES IN HUMAN LYSOZYME CO-CRYSTALLIZED WITH HEXA-N-ACETYL-CHITOHEXAOSE AT PH 4.0

ChemComp-I2U:
5-chloranyl-2-oxidanyl-3-thiophen-2-ylcarbonyl-indole-1-carboxamide / antiinflammatory, inhibitor*YM

Source
  • homo sapiens (human)
KeywordsMEMBRANE PROTEIN / Chloride anion exchanger

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