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Structure paper

TitleSelective ligand recognition and activation of somatostatin receptors SSTR1 and SSTR3
Journal, issue, pagesTo Be Published
Publish dateDec 19, 2023 (structure data deposition date)
AuthorsWang Y / Xu Y / He X / Fan W / Wu K / Hu W / Cheng X / Sun S / Xu HE / Zhuang Y
External linksSearch PubMed
MethodsEM (single particle)
Resolution2.52 - 3.29 Å
Structure data

38385

8xio

EMDB-38385, PDB-8xio:
Structure of L797591-SSTR1 G protein complex
Method: EM (single particle) / Resolution: 2.65 Å

38386

8xip

EMDB-38386, PDB-8xip:
Structure of Pasireotide-SSTR1 G protein complex
Method: EM (single particle) / Resolution: 3.29 Å

38387

8xiq

EMDB-38387, PDB-8xiq:
Structure of L796778-SSTR3 G protein complex
Method: EM (single particle) / Resolution: 2.71 Å

38388

8xir

EMDB-38388, PDB-8xir:
Structure of pasireotide-SSTR3 G protein complex
Method: EM (single particle) / Resolution: 2.52 Å

Chemicals

PDB-1d5d:
The role of phenylalanine 8 in the stabilization of the s protein-s peptide interaction: packing and cavities

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
  • lama glama (llama)
  • synthetic construct (others)
KeywordsMEMBRANE PROTEIN/IMMUNE SYSTEM / GPCR / SSTR1 / L797591 / MEMBRANE PROTEIN-IMMUNE SYSTEM complex / pasireotide / MEMBRANE PROTEIN / SSTR3 / L796778

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