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TitleAu4 cluster inhibits human thioredoxin reductase activity via specifically binding of Au to Cys189
Journal, issue, pagesNano Today, Vol. 47, Page 101686, Year 2022
Publish dateFeb 24, 2022 (structure data deposition date)
AuthorsDu Z / He Z / Fan J / Huo Y / He B / Wang Y / Sun Q / Niu W / Zhao W / Zhao L ...Du Z / He Z / Fan J / Huo Y / He B / Wang Y / Sun Q / Niu W / Zhao W / Zhao L / Cao P / Cao K / Xia D / Yuan Q / Liang XJ / Jiang H / Gong Y / Gao X
External linksNano Today / Search PubMed
MethodsEM (single particle)
Resolution3.9 Å
Structure data

32947

7x1r

EMDB-32947, PDB-7x1r:
Cryo-EM structure of human thioredoxin reductase bound by Au
Method: EM (single particle) / Resolution: 3.9 Å

Chemicals

ChemComp-FAD:
FLAVIN-ADENINE DINUCLEOTIDE / FAD*YM

ChemComp-AU:
Unknown entry

Source
  • homo sapiens (human)
KeywordsOXIDOREDUCTASE / PROTEIN-METAL COMPLEX / HOMODIMERIC / REDOX-ACTIVE CENTER / FAD

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