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-Structure paper
Title | Cryo-EM structure of Mtb Lpd bound to the inhibitor 2-((2-cyano-N,5-dimethyl-1H-indole)-7-sulfonamido)-N-(4-(oxetan-3-yl)-3,4-dihydro-2H-benzo[b] [1,4]oxazin-7-yl)acetamide at 2.17 Angstrom resolution |
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Journal, issue, pages | Not published |
Publish date | May 13, 2022 (structure data deposition date) |
Authors | Kochanczyk T / Arango N / Michino M / Sun S / Ginn J / Bryk R / Nathan C / Lima CD |
External links | Search PubMed |
Methods | EM (single particle) |
Resolution | 2.17 Å |
Structure data | EMDB-26981, PDB-8ct4: |
Chemicals | ChemComp-FAD: ChemComp-OU6: ChemComp-HOH: |
Source |
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Keywords | OXIDOREDUCTASE/INHIBITOR / flavoprotein / glycolysis / redox-active center / OXIDOREDUCTASE-INHIBITOR complex |