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-Structure paper
Title | Limited breadth of anti-HIV Env glycan hole antibodies is further hindered by strain-specific peptide interactions |
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Journal, issue, pages | To Be Published |
Publish date | Jun 2, 2020 (structure data deposition date) |
Authors | Ozorowski, G. / Cottrell, C.A. / Oyen, D. / de Val, N. / Copps, J. / Scaring, N. / Polveroni, T.M. / Wilson, I.A. / Ward, A.B. |
External links | Search PubMed |
Methods | EM (single particle) / X-ray diffraction |
Resolution | 2.2 - 3.65 Å |
Structure data | EMDB-22102: Cryo-EM reconstruction of HIV-1 Env BG505 SOSIP.664 in complex with rabbit monoclonal antibody 10A fragment antigen binding EMDB-22103: Cryo-EM reconstruction of HIV-1 Env BG505 SOSIP.664 in complex with rabbit monoclonal antibody 11A fragment antigen binding EMDB-22104: Cryo-EM reconstruction of HIV-1 Env BG505 SOSIP.664 in complex with rabbit monoclonal antibody 11B fragment antigen binding PDB-7ra7: |
Chemicals | ChemComp-NAG: ChemComp-SO4: ChemComp-1PE: ChemComp-HOH: |
Source |
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Keywords | VIRAL PROTEIN/IMMUNE SYSTEM / HIV-1 / Env / glycan hole / antibody / vaccine design / VIRAL PROTEIN-IMMUNE SYSTEM complex / IMMUNE SYSTEM / antibody antigen neutralizing antibody HIV |