EMDB/PDB/SASBDBから引用されている文献のデータベース

キーワード
構造解析手法	All X線回折 NMR 電子顕微鏡小角散乱中性子線回折線維回折粉末回折赤外分光 EPR FRET 理論モデルハイブリッド
著者・登録者
ジャーナル
IF	>30 >20 >10 >5 all

タイトル	Synthesis and evaluation of chemical linchpins for highly selective CK2 alpha targeting.
ジャーナル・号・ページ	Eur. J. Med. Chem., Vol. 276, Page 116672-116672, Year 2024
掲載日	2023年7月18日 (構造データの登録日)
著者	Greco, F.A. / Kramer, A. / Wahl, L. / Elson, L. / Ehret, T.A.L. / Gerninghaus, J. / Mockel, J. / Muller, S. / Hanke, T. / Knapp, S.
リンク	Eur. J. Med. Chem. / PubMed:39067440
手法	X線回折
解像度	2 - 3.15 Å
構造データ	PDB-8pvo: Crystal structure of human Casein Kinase II subunit alpha (CK2a1) in complex with allosteric compound FG5 手法: X-RAY DIFFRACTION / 解像度: 2.25 Å PDB-8pvp: Crystal structure of human Casein Kinase II subunit alpha (CK2a1) in complex with allosteric compound FGJG18 手法: X-RAY DIFFRACTION / 解像度: 2.6 Å PDB-8rdk: Crystal structure of human Haspin (GSG2) kinase bound to MD420 手法: X-RAY DIFFRACTION / 解像度: 2.0 Å PDB-9epv: Crystal structure of human Casein Kinase II subunit alpha (CK2a1) in complex with allosteric ligand FGC333 手法: X-RAY DIFFRACTION / 解像度: 2.3 Å PDB-9epw: Crystal structure of human Casein Kinase II subunit alpha (CK2a1) in complex with allosteric ligand FGC3336 手法: X-RAY DIFFRACTION / 解像度: 2.3 Å PDB-9epy: Crystal structure of human Casein Kinase II subunit alpha (CK2a1) in complex with allosteric ligand FGC3330 手法: X-RAY DIFFRACTION / 解像度: 2.65 Å PDB-9epz: Crystal structure of human Casein Kinase II subunit alpha (CK2a1) in complex with allosteric ligand FGC3337 手法: X-RAY DIFFRACTION / 解像度: 2.65 Å PDB-9eq0: Crystal structure of human Casein Kinase II subunit alpha (CK2a1) in complex with allosteric ligand FGJG12 手法: X-RAY DIFFRACTION / 解像度: 3.15 Å PDB-9eq1: Crystal structure of human Casein Kinase II subunit alpha (CK2a1) in complex with allosteric ligand FGJM24 手法: X-RAY DIFFRACTION / 解像度: 3.0 Å
化合物	ChemComp-SO4: SULFATE ION / 硫酸ジアニオン ChemComp-EDO: 1,2-ETHANEDIOL / エチレングリコ-ル ChemComp-FW3: 2-[1-(1,3-benzothiazol-6-ylsulfonyl)piperidin-4-yl]-~{N}-[(3-chloranyl-4-phenyl-phenyl)methyl]ethanamine ChemComp-NA: Unknown entry / ナトリウムカチオン ChemComp-HOH: WATER ChemComp-FWU: ~{N}-[5-[(3-chloranyl-4-phenyl-phenyl)methylamino]pentyl]isoquinoline-5-sulfonamide ChemComp-ZN: Unknown entry ChemComp-MPD: (4S)-2-METHYL-2,4-PENTANEDIOL / (S)-2-メチル-2,4-ペンタンジオ-ル / 沈殿剤YM 化合物画像なし ChemComp-YQT: Unknown entry PDB-1h6h: Structure of the PX domain from p40phox bound to phosphatidylinositol 3-phosphate PDB-1h6f: Human TBX3, a transcription factor responsible for ulnar-mammary syndrome, bound to a palindromic DNA site PDB-1h6g: alpha-catenin M-domain PDB-1h6i: A REFINED STRUCTURE OF HUMAN AQUAPORIN 1 PDB-1h6d: Oxidized Precursor Form of Glucose-Fructose Oxidoreductase from Zymomonas mobilis complexed with glycerol PDB-1h6j*: The three-dimensional structure of capsule-specific CMP:2-keto-3-deoxy-manno-octonic acid synthetase from Escherichia coli
由来	homo sapiens (ヒト)
キーワード	TRANSFERASE / Kinase / CK2 / Allosteric Inhibitor / Haspin / Inhibitor / Chemical