EMDB/PDB/SASBDBから引用されている文献のデータベース

キーワード
構造解析手法	All X線回折 NMR 電子顕微鏡小角散乱中性子線回折線維回折粉末回折赤外分光 EPR FRET 理論モデルハイブリッド
著者・登録者
ジャーナル
IF	>30 >20 >10 >5 all

タイトル	Screening a knowledge-based library of low molecular weight compounds against the proline biosynthetic enzyme 1-pyrroline-5-carboxylate 1 (PYCR1).
ジャーナル・号・ページ	Protein Sci., Vol. 33, Page e5072-e5072, Year 2024
掲載日	2023年7月2日 (構造データの登録日)
著者	Meeks, K.R. / Bogner, A.N. / Tanner, J.J.
リンク	Protein Sci. / PubMed:39133178
手法	X線回折
解像度	1.42 - 2.3 Å
構造データ	PDB-8td2: Structure of PYCR1 complexed with NADH and cyclobutane-1,1-dicarboxylic acid 手法: X-RAY DIFFRACTION / 解像度: 1.65 Å PDB-8td3: Structure of PYCR1 complexed with NADH and (S)-Tetrahydro-2H-pyran-2-carboxylic acid 手法: X-RAY DIFFRACTION / 解像度: 1.67 Å PDB-8td4: Structure of PYCR1 complexed with NADH and 1,3-Dithiolane-2-carboxylic acid 手法: X-RAY DIFFRACTION / 解像度: 1.76 Å PDB-8td5: Structure of PYCR1 complexed with NADH and Tetrahydrothiophene-2-carboxylic acid 手法: X-RAY DIFFRACTION / 解像度: 1.81 Å PDB-8td6: Structure of PYCR1 complexed with NADH and 2-(Methylthio)acetic acid 手法: X-RAY DIFFRACTION / 解像度: 2.08 Å PDB-8td7: Structure of PYCR1 complexed with 2S-hydroxy-3-methylbutyric acid 手法: X-RAY DIFFRACTION / 解像度: 1.61 Å PDB-8td8: Structure of PYCR1 complexed with NADH and 2S-Hydroxy-3,3-dimethylbutyric acid 手法: X-RAY DIFFRACTION / 解像度: 1.71 Å PDB-8td9: Structure of PYCR1 complexed with NADH and L-pipecolic acid 手法: X-RAY DIFFRACTION / 解像度: 1.75 Å PDB-8tdb: Structure of PYCR1 complexed with NADH and 1-hydroxyethane-1-sulfonate 手法: X-RAY DIFFRACTION / 解像度: 2.3 Å PDB-8tdc: Structure of PYCR1 complexed with NADH and 1,3-dithiane-2-carboxylic acid 手法: X-RAY DIFFRACTION / 解像度: 1.8 Å PDB-8tdd: Structure of PYCR1 complexed with NADH and 2-(furan-2-yl)acetic acid 手法: X-RAY DIFFRACTION / 解像度: 1.91 Å PDB-8vre: Structure of PYCR1 complexed with NADH and N-formyl-L-proline 手法: X-RAY DIFFRACTION / 解像度: 1.83 Å PDB-8w0k: Minimal PutA proline dehydrogenase domain (design #2) complexed with 1-hydroxyethane-1-sulfonate 手法: X-RAY DIFFRACTION / 解像度: 1.42 Å
化合物	ChemComp-NAI: 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE ChemComp-ZPS: cyclobutane-1,1-dicarboxylic acid ChemComp-SO4: SULFATE ION ChemComp-HOH: WATER 化合物画像なし ChemComp-GJM: Unknown entry ChemComp-PEG: DI(HYDROXYETHYL)ETHER ChemComp-PGE: TRIETHYLENE GLYCOL ChemComp-UJD: 1,3-dithiolane-2-carboxylic acid ChemComp-UJP: (2R)-thiolane-2-carboxylic acid ChemComp-MTG: [METHYLTHIO]ACETATE ChemComp-LHV: (2S)-2-hydroxy-3-methylbutanoic acid 化合物画像なし ChemComp-G8I: Unknown entry ChemComp-YCP: (2S)-piperidine-2-carboxylic acid 化合物画像なし ChemComp-GHO: Unknown entry 化合物画像なし ChemComp-GIW: Unknown entry ChemComp-SJU: (furan-2-yl)acetic acid ChemComp-FPK: 1-formyl-L-proline ChemComp-FAD: FLAVIN-ADENINE DINUCLEOTIDE / FAD*YM
由来	homo sapiens (ヒト) sinorhizobium meliloti sm11 (根粒菌)
キーワード	OXIDOREDUCTASE/INHIBITOR / AMINO-ACID BIOSYNTHESIS / OXIDOREDUCTASE / PROLINE BIOSYNTHESIS / OXIDOREDUCTASE-INHIBITOR complex / BETA/ALPHA BARREL / FLAVOENZYME / PROLINE CATABOLISM