EMDB/PDB/SASBDBから引用されている文献のデータベース

キーワード
構造解析手法	All X線回折 NMR 電子顕微鏡小角散乱中性子線回折線維回折粉末回折赤外分光 EPR FRET 理論モデルハイブリッド
著者・登録者
ジャーナル
IF	>30 >20 >10 >5 all

タイトル	A structural basis for metal ion mutagenicity and nucleotide selectivity in human DNA polymerase beta
ジャーナル・号・ページ	Biochemistry, Vol. 35, Page 12762-12777, Year 1996
掲載日	1996年4月12日 (構造データの登録日)
著者	Pelletier, H. / Sawaya, M.R. / Wolfle, W. / Wilson, S.H. / Kraut, J.
リンク	Biochemistry / PubMed:8841119
手法	X線回折
解像度	2.7 - 3.5 Å
構造データ	PDB-1zqt: DNA POLYMERASE BETA (POL B) (E.C.2.7.7.7) COMPLEXED WITH SEVEN BASE PAIRS OF DNA; SOAKED IN THE PRESENCE OF DATP (0.01 MILLIMOLAR) AND ZNCL2 (0.02 MILLIMOLAR) 手法: X-RAY DIFFRACTION / 解像度: 3.4 Å PDB-7ice: DNA POLYMERASE BETA (E.C.2.7.7.7)/DNA COMPLEX, SOAKED IN THE PRESENCE OF CACL2 手法: X-RAY DIFFRACTION / 解像度: 2.8 Å PDB-7icf: DNA POLYMERASE BETA (POL B) (E.C.2.7.7.7) COMPLEXED WITH SIX BASE PAIRS OF DNA; SOAKED IN THE PRESENCE OF CDCL2 (0.1 MILLIMOLAR) (FOUR-DAY SOAK) 手法: X-RAY DIFFRACTION / 解像度: 3.1 Å PDB-7icg: DNA POLYMERASE BETA (E.C.2.7.7.7)/DNA COMPLEX, SOAKED IN THE PRESENCE OF CDCL2 手法: X-RAY DIFFRACTION / 解像度: 3.0 Å PDB-7ich: DNA POLYMERASE BETA (E.C.2.7.7.7)/DNA COMPLEX, SOAKED IN THE PRESENCE OF COCL2 手法: X-RAY DIFFRACTION / 解像度: 2.9 Å PDB-7ici: DNA POLYMERASE BETA (POL B) (E.C.2.7.7.7) COMPLEXED WITH SIX BASE PAIRS OF DNA; SOAKED IN THE PRESENCE OF CRCL3 (0.1 MILLIMOLAR) 手法: X-RAY DIFFRACTION / 解像度: 2.8 Å PDB-7icj: DNA POLYMERASE BETA (POL B) (E.C.2.7.7.7) COMPLEXED WITH SIX BASE PAIRS OF DNA; SOAKED IN THE PRESENCE OF CUCL2 (0.1 MILLIMOLAR) 手法: X-RAY DIFFRACTION / 解像度: 3.5 Å PDB-7ick: DNA POLYMERASE BETA (E.C.2.7.7.7)/DNA COMPLEX, SOAKED IN THE PRESENCE OF MGCL2 手法: X-RAY DIFFRACTION / 解像度: 2.9 Å PDB-7icl: DNA POLYMERASE BETA (POL B) (E.C.2.7.7.7) COMPLEXED WITH SIX BASE PAIRS OF DNA; SOAKED IN THE PRESENCE OF MNCL2 (0.1 MILLIMOLAR) 手法: X-RAY DIFFRACTION / 解像度: 3.1 Å PDB-7icm: DNA POLYMERASE BETA (POL B) (E.C.2.7.7.7) COMPLEXED WITH SIX BASE PAIRS OF DNA; SOAKED IN THE PRESENCE OF MNCL2 (1.0 MILLIMOLAR) 手法: X-RAY DIFFRACTION / 解像度: 3.0 Å PDB-7icn: DNA POLYMERASE BETA (E.C.2.7.7.7)/DNA COMPLEX, SOAKED IN THE PRESENCE OF NICL2 手法: X-RAY DIFFRACTION / 解像度: 2.8 Å PDB-7ico: DNA POLYMERASE BETA (E.C.2.7.7.7)/DNA COMPLEX, SOAKED IN THE PRESENCE OF ZNCL2 手法: X-RAY DIFFRACTION / 解像度: 3.3 Å PDB-7icp: DNA POLYMERASE BETA (POL B) (E.C.2.7.7.7) COMPLEXED WITH SIX BASE PAIRS OF DNA; SOAKED IN THE PRESENCE OF ZNCL2 (0.01 MILLIMOLAR) 手法: X-RAY DIFFRACTION / 解像度: 3.0 Å PDB-7icq: DNA POLYMERASE BETA (E.C.2.7.7.7)/DNA COMPLEX, SOAKED IN THE PRESENCE OF ZNCL2 手法: X-RAY DIFFRACTION / 解像度: 2.9 Å PDB-7icr: DNA POLYMERASE BETA (E.C.2.7.7.7)/DNA COMPLEX, SOAKED IN THE PRESENCE OF ZNCL2 手法: X-RAY DIFFRACTION / 解像度: 3.0 Å PDB-7ics: DNA POLYMERASE BETA (E.C.2.7.7.7)/DNA COMPLEX, SOAKED IN THE PRESENCE OF ZNCL2 手法: X-RAY DIFFRACTION / 解像度: 2.8 Å PDB-7ict: DNA POLYMERASE BETA (E.C.2.7.7.7)/DNA COMPLEX, SOAKED IN THE PRESENCE OF ZNCL2 AND MGCL2 手法: X-RAY DIFFRACTION / 解像度: 2.8 Å PDB-7icu: DNA POLYMERASE BETA (POL B) (E.C.2.7.7.7) COMPLEXED WITH SIX BASE PAIRS OF DNA; SOAKED IN THE PRESENCE OF CDCL2 (0.1 MILLIMOLAR) 手法: X-RAY DIFFRACTION / 解像度: 3.3 Å PDB-7icv: DNA POLYMERASE BETA (POL B) (E.C.2.7.7.7) COMPLEXED WITH SIX BASE PAIRS OF DNA; SOAKED IN THE PRESENCE OF MNCL2 (0.1 MILLIMOLAR) AND IN THE ABSENCE OF NACL 手法: X-RAY DIFFRACTION / 解像度: 2.8 Å PDB-8icj: DNA POLYMERASE BETA (E.C.2.7.7.7)/DNA COMPLEX + THYMIDINE-5'-TRIPHOSPHATE, SOAKED IN THE PRESENCE OF DTTP AND MGCL2 手法: X-RAY DIFFRACTION / 解像度: 3.2 Å PDB-8ick: DNA POLYMERASE BETA (POL B) (E.C.2.7.7.7) COMPLEXED WITH SEVEN BASE PAIRS OF DNA; SOAKED IN THE PRESENCE OF DATP (1 MILLIMOLAR), MGCL2 (5 MILLIMOLAR), AND MNCL2 (5 MILLIMOLAR) 手法: X-RAY DIFFRACTION / 解像度: 2.7 Å PDB-8icl: DNA POLYMERASE BETA (POL B) (E.C.2.7.7.7) COMPLEXED WITH SEVEN BASE PAIRS OF DNA; SOAKED IN THE PRESENCE OF DATP (1 MILLIMOLAR) AND NICL2 (5 MILLIMOLAR) 手法: X-RAY DIFFRACTION / 解像度: 3.1 Å PDB-8icm: DNA POLYMERASE BETA (POL B) (E.C.2.7.7.7) COMPLEXED WITH SEVEN BASE PAIRS OF DNA; SOAKED IN THE PRESENCE OF DATP (1 MILLIMOLAR), MNCL2 (5 MILLIMOLAR), AND AMMONIUM SULFATE (75 MILLIMOLAR) 手法: X-RAY DIFFRACTION / 解像度: 2.9 Å PDB-8icn: DNA POLYMERASE BETA (POL B) (E.C.2.7.7.7) COMPLEXED WITH SEVEN BASE PAIRS OF DNA; SOAKED IN THE PRESENCE OF ATP (1 MILLIMOLAR) AND MNCL2 (5 MILLIMOLAR) 手法: X-RAY DIFFRACTION / 解像度: 2.8 Å PDB-8ico: DNA POLYMERASE BETA (POL B) (E.C.2.7.7.7) COMPLEXED WITH SEVEN BASE PAIRS OF DNA; SOAKED IN THE PRESENCE OF AZT-TP (1 MILLIMOLAR) AND MNCL2 (5 MILLIMOLAR) 手法: X-RAY DIFFRACTION / 解像度: 2.7 Å PDB-8icp: DNA POLYMERASE BETA (POL B) (E.C.2.7.7.7) COMPLEXED WITH SEVEN BASE PAIRS OF DNA; SOAKED IN THE PRESENCE OF DATP (1 MILLIMOLAR) AND MNCL2 (5 MILLIMOLAR) 手法: X-RAY DIFFRACTION / 解像度: 2.9 Å PDB-8icq: DNA POLYMERASE BETA (POL B) (E.C.2.7.7.7) COMPLEXED WITH SEVEN BASE PAIRS OF DNA; SOAKED IN THE PRESENCE OF OF DATP (0.1 MILLIMOLAR) AND MNCL2 (0.5 MILLIMOLAR) 手法: X-RAY DIFFRACTION / 解像度: 3.0 Å PDB-8icr: DNA POLYMERASE BETA (POL B) (E.C.2.7.7.7) COMPLEXED WITH SEVEN BASE PAIRS OF DNA; SOAKED IN THE PRESENCE OF DATP (1 MILLIMOLAR) AND MNCL2 (5 MILLIMOLAR) 手法: X-RAY DIFFRACTION / 解像度: 2.9 Å PDB-8ics: DNA POLYMERASE BETA (POL B) (E.C.2.7.7.7) COMPLEXED WITH SEVEN BASE PAIRS OF DNA; SOAKED IN THE PRESENCE OF DCTP (1 MILLIMOLAR) AND MNCL2 (5 MILLIMOLAR) 手法: X-RAY DIFFRACTION / 解像度: 2.9 Å PDB-8ict: DNA POLYMERASE BETA (POL B) (E.C.2.7.7.7) COMPLEXED WITH SEVEN BASE PAIRS OF DNA; SOAKED IN THE PRESENCE OF DCTP (1 MILLIMOLAR) AND MNCL2 (5 MILLIMOLAR) 手法: X-RAY DIFFRACTION / 解像度: 3.1 Å PDB-8icu: DNA POLYMERASE BETA (POL B) (E.C.2.7.7.7) COMPLEXED WITH SEVEN BASE PAIRS OF DNA; SOAKED IN THE PRESENCE OF DDATP (1 MILLIMOLAR) AND MNCL2 (5 MILLIMOLAR) 手法: X-RAY DIFFRACTION / 解像度: 3.0 Å PDB-8icv: DNA POLYMERASE BETA (POL B) (E.C.2.7.7.7) COMPLEXED WITH SEVEN BASE PAIRS OF DNA; SOAKED IN THE PRESENCE OF DGTP (1 MILLIMOLAR) AND MNCL2 (5 MILLIMOLAR) 手法: X-RAY DIFFRACTION / 解像度: 3.2 Å PDB-8icw: DNA POLYMERASE BETA (POL B) (E.C.2.7.7.7) COMPLEXED WITH SEVEN BASE PAIRS OF DNA; SOAKED IN THE PRESENCE OF DTTP (1 MILLIMOLAR) AND MNCL2 (5 MILLIMOLAR) 手法: X-RAY DIFFRACTION / 解像度: 3.3 Å PDB-8icx: DNA POLYMERASE BETA (POL B) (E.C.2.7.7.7) COMPLEXED WITH SEVEN BASE PAIRS OF DNA; SOAKED IN THE PRESENCE OF DTTP (1 MILLIMOLAR) AND MNCL2 (5 MILLIMOLAR) 手法: X-RAY DIFFRACTION / 解像度: 3.0 Å PDB-8icy: DNA POLYMERASE BETA (E.C.2.7.7.7)/DNA COMPLEX + THYMIDINE-5'-TRIPHOSPHATE, SOAKED IN THE PRESENCE OF DTTP AND MNCL2 手法: X-RAY DIFFRACTION / 解像度: 3.1 Å PDB-9icf: DNA POLYMERASE BETA (E.C.2.7.7.7)/DNA COMPLEX + 2'-DEOXYADENOSINE-5'-TRIPHOSPHATE, SOAKED IN THE PRESENCE OF DATP AND ZNCL2 手法: X-RAY DIFFRACTION / 解像度: 3.0 Å PDB-9ick: DNA POLYMERASE BETA (E.C.2.7.7.7)/DNA COMPLEX, SOAKED IN THE PRESENCE OF ARTIFICIAL MOTHER LIQUOR 手法: X-RAY DIFFRACTION / 解像度: 2.7 Å PDB-9icn: DNA POLYMERASE BETA (E.C.2.7.7.7)/DNA COMPLEX + 2',3'-DIDEOXYCYTIDINE-5'-TRIPHOSPHATE, SOAKED IN THE PRESENCE OF DDCTP AND MGCL2 手法: X-RAY DIFFRACTION / 解像度: 3.0 Å PDB-9ico: DNA POLYMERASE BETA (E.C.2.7.7.7)/DNA COMPLEX, SOAKED IN THE PRESENCE OF DTTP AND MGCL2 手法: X-RAY DIFFRACTION / 解像度: 2.9 Å PDB-9icp: DNA POLYMERASE BETA (POL B) (E.C.2.7.7.7) COMPLEXED WITH SIX BASE PAIRS OF DNA; SOAKED IN THE PRESENCE OF PYROPHOSPHATE (1 MILLIMOLAR) AND MGCL2 (5 MILLIMOLAR) 手法: X-RAY DIFFRACTION / 解像度: 3.1 Å PDB-9icq: DNA POLYMERASE BETA (POL B) (E.C.2.7.7.7) COMPLEXED WITH SIX BASE PAIRS OF DNA; SOAKED IN THE PRESENCE OF DATP (1 MILLIMOLAR) AND MNCL2 (5 MILLIMOLAR) 手法: X-RAY DIFFRACTION / 解像度: 2.9 Å PDB-9icr: DNA POLYMERASE BETA (E.C.2.7.7.7)/DNA COMPLEX + 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, SOAKED IN THE PRESENCE OF DCTP AND MNCL2 手法: X-RAY DIFFRACTION / 解像度: 3.0 Å PDB-9ics: DNA POLYMERASE BETA (E.C.2.7.7.7)/DNA COMPLEX + 2',3'-DIDEOXYCYTIDINE-5'-TRIPHOSPHATE, SOAKED IN THE PRESENCE OF DDCTP AND MNCL2 手法: X-RAY DIFFRACTION / 解像度: 2.9 Å PDB-9ict: DNA POLYMERASE BETA (E.C.2.7.7.7)/DNA COMPLEX + 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, SOAKED IN THE PRESENCE OF DGTP AND MNCL2 手法: X-RAY DIFFRACTION / 解像度: 3.0 Å PDB-9icu: DNA POLYMERASE BETA (POL B) (E.C.2.7.7.7) COMPLEXED WITH SIX BASE PAIRS OF DNA; SOAKED IN THE PRESENCE OF DTTP (1 MILLIMOLAR) AND MNCL2 (5 MILLIMOLAR) 手法: X-RAY DIFFRACTION / 解像度: 2.9 Å PDB-9icv: DNA POLYMERASE BETA (E.C.2.7.7.7)/DNA COMPLEX + 2'-DEOXYADENOSINE-5'-TRIPHOSPHATE, SOAKED IN THE PRESENCE OF DATP AND ZNCL2 手法: X-RAY DIFFRACTION / 解像度: 2.7 Å
化合物	ChemComp-ZN: Unknown entry ChemComp-NA: Unknown entry / ナトリウムカチオン ChemComp-HOH: WATER / 水 ChemComp-CD: Unknown entry ChemComp-CU: COPPER (II) ION / 銅 ChemComp-TTP: THYMIDINE-5'-TRIPHOSPHATE / dTTP / チミジン三リン酸 ChemComp-MN: Unknown entry ChemComp-DTP: 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE / dATP / デオキシアデノシン三リン酸 ChemComp-NI: NICKEL (II) ION / ニッケル ChemComp-SO4: SULFATE ION / 硫酸ジアニオン / 硫酸塩 ChemComp-ATP: ADENOSINE-5'-TRIPHOSPHATE / ATP / ATP, エネルギー貯蔵分子YM / アデノシン三リン酸 ChemComp-AZT: 3'-AZIDO-3'-DEOXYTHYMIDINE-5'-TRIPHOSPHATE / AZTTP ChemComp-DCP: 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE / dCTP / デオキシシチジン三リン酸 ChemComp-DAD: 2',3'-DIDEOXYADENOSINE-5'-TRIPHOSPHATE / 1-(6-アミノ-9H-プリン-9-イル)-1,2,3-トリデオキシ-β-L-リボフラノ-ス5-三りん酸 ChemComp-DGT: 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE / dGTP / デオキシグアノシン三リン酸 ChemComp-MG: Unknown entry / マグネシウムジカチオン ChemComp-DCT*: 2',3'-DIDEOXYCYTIDINE 5'-TRIPHOSPHATE / ddCTP
由来	homo sapiens (ヒト)
キーワード	TRANSFERASE/DNA / DNA-DIRECTED DNA POLYMERASE (DNAポリメラーゼ) / DNA REPLICATION (DNA複製) / DNA REPAIR (DNA修復) / NUCLEOTIDYLTRANSFERASE / COMPLEX (NUCLEOTIDYLTRANSFERASE-DNA / TRANSFERASE-DNA complex / COMPLEX (NUCLEOTIDYLTRANSFERASE-DNA)