タイトル | A partially open conformation of an androgen receptor ligand-binding domain with drug-resistance mutations. |
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ジャーナル・号・ページ | Acta Crystallogr. ,Sect. F, Vol. 79, Page 95-104, Year 2023 |
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掲載日 | 2022年12月13日 (構造データの登録日) |
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著者 | Doamekpor, S.K. / Peng, P. / Xu, R. / Ma, L. / Tong, Y. / Tong, L. |
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リンク | Acta Crystallogr. ,Sect. F / PubMed:36995121 |
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手法 | X線回折 |
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解像度 | 1.59 - 2.2 Å |
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構造データ | PDB-8fgy: Crystal structure of mutant Androgen Receptor ligand binding domain L702H/H875Y/F877L/T878A with DHT 手法: X-RAY DIFFRACTION / 解像度: 2.2 Å PDB-8fgz: Crystal structure of mutant Androgen Receptor ligand binding domain L702H/H875Y/F877L with DHT 手法: X-RAY DIFFRACTION / 解像度: 1.61 Å PDB-8fh0: Crystal structure of mutant Androgen Receptor ligand binding domain H875Y/F877L/T878A with DHT 手法: X-RAY DIFFRACTION / 解像度: 1.59 Å PDB-8fh1: Crystal structure of mutant Androgen Receptor ligand binding domain F877L/T878A with DHT 手法: X-RAY DIFFRACTION / 解像度: 1.69 Å PDB-8fh2: Crystal structure of mutant Androgen Receptor ligand binding domain L702H/H875Y with DHT 手法: X-RAY DIFFRACTION / 解像度: 1.59 Å |
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化合物 | |
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由来 | homo sapiens (ヒト)
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キーワード | GENE REGULATION / AR / Androgen receptor / DHT / steroid receptor |
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