タイトル | Molecular determinants of cross-reactivity and potency by VH3-33 antibodies against the Plasmodium falciparum circumsporozoite protein. |
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ジャーナル・号・ページ | Cell Rep, Vol. 42, Page 113330-113330, Year 2023 |
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掲載日 | 2022年11月23日 (構造データの登録日) |
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著者 | Thai, E. / Murugan, R. / Binter, S. / Burn Aschner, C. / Prieto, K. / Kassardjian, A. / Obraztsova, A.S. / Kang, R.W. / Flores-Garcia, Y. / Mathis-Torres, S. ...Thai, E. / Murugan, R. / Binter, S. / Burn Aschner, C. / Prieto, K. / Kassardjian, A. / Obraztsova, A.S. / Kang, R.W. / Flores-Garcia, Y. / Mathis-Torres, S. / Li, K. / Horn, G.Q. / Huntwork, R.H.C. / Bolscher, J.M. / de Bruijni, M.H.C. / Sauerwein, R. / Dennison, S.M. / Tomaras, G.D. / Zavala, F. / Kellam, P. / Wardemann, H. / Julien, J.P. |
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リンク | Cell Rep / PubMed:38007690 |
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手法 | X線回折 |
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解像度 | 1.54 - 2.95 Å |
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構造データ | PDB-8f95: Crystal structure of Ky15.2 Fab in complex with circumsporozoite protein DND peptide 手法: X-RAY DIFFRACTION / 解像度: 2.45 Å PDB-8f9e: Crystal structure of Ky15.2 Fab in complex with circumsporozoite protein KQPA peptide 手法: X-RAY DIFFRACTION / 解像度: 2.95 Å PDB-8f9f: Crystal structure of Ky15.2 Fab in complex with circumsporozoite protein NANP3 peptide 手法: X-RAY DIFFRACTION / 解像度: 2.2 Å PDB-8f9s: Crystal structure of Ky15.2 Fab in complex with circumsporozoite protein NDN peptide 手法: X-RAY DIFFRACTION / 解像度: 2.1 Å PDB-8f9t: Crystal structure of Ky15.2 Fab in complex with circumsporozoite protein NPDP peptide 手法: X-RAY DIFFRACTION / 解像度: 1.85 Å PDB-8f9u: Crystal structure of Ky15.7 Fab in complex with circumsporozoite protein NPDP peptide 手法: X-RAY DIFFRACTION / 解像度: 1.7 Å PDB-8f9v: Crystal structure of Ky15.8 Fab in complex with circumsporozoite protein KQPA peptide 手法: X-RAY DIFFRACTION / 解像度: 2.25 Å PDB-8f9w: Crystal structure of Ky15.8 Fab in complex with circumsporozoite protein NPDP peptide 手法: X-RAY DIFFRACTION / 解像度: 2.4 Å PDB-8fa6: Crystal structure of Ky15.10 Fab in complex with circumsporozoite protein DND peptide 手法: X-RAY DIFFRACTION / 解像度: 2.6 Å PDB-8fa7: Crystal structure of Ky15.11 Fab in complex with circumsporozoite protein KQPA peptide 手法: X-RAY DIFFRACTION / 解像度: 1.8 Å PDB-8fa8: Crystal structure of Ky15.11 Fab in complex with circumsporozoite protein NDN peptide 手法: X-RAY DIFFRACTION / 解像度: 1.8 Å PDB-8fa9: Crystal structure of Ky15.5 Fab in complex with circumsporozoite protein NPDP peptide 手法: X-RAY DIFFRACTION / 解像度: 2.45 Å PDB-8fan: Crystal structure of Ky15.1 Fab in complex with circumsporozoite protein KQPA peptide 手法: X-RAY DIFFRACTION / 解像度: 2.9 Å PDB-8fas: Crystal structure of Ky230 Fab in complex with circumsporozoite protein NANP5 peptide 手法: X-RAY DIFFRACTION / 解像度: 1.55 Å PDB-8fat: Crystal structure of Ky224 Fab in complex with circumsporozoite protein NPDP peptide 手法: X-RAY DIFFRACTION / 解像度: 2.95 Å PDB-8fb5: Crystal structure of Ky15.11-S100IK Fab in complex with circumsporozoite protein KQPA peptide 手法: X-RAY DIFFRACTION / 解像度: 2.9 Å PDB-8fb6: Crystal structure of Ky15.10 Fab in complex with circumsporozoite protein KQPA peptide 手法: X-RAY DIFFRACTION / 解像度: 2.15 Å PDB-8fb7: Crystal structure of Ky15.10 Fab in complex with circumsporozoite protein NPDP peptide 手法: X-RAY DIFFRACTION / 解像度: 1.75 Å PDB-8fb8: Crystal structure of Ky15.10-Y100EK Fab in complex with circumsporozoite protein KQPA peptide 手法: X-RAY DIFFRACTION / 解像度: 1.69 Å PDB-8fba: Crystal structure of Ky315 Fab in complex with circumsporozoite protein DND peptide 手法: X-RAY DIFFRACTION / 解像度: 1.96 Å PDB-8fdc: Crystal structure of Ky311 Fab in complex with circumsporozoite protein KQPA peptide 手法: X-RAY DIFFRACTION / 解像度: 1.8 Å PDB-8fdd: Crystal structure of Ky15.3 Fab in complex with circumsporozoite protein NPDP peptide 手法: X-RAY DIFFRACTION / 解像度: 1.54 Å |
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化合物 | |
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由来 | - mus musculus (ハツカネズミ)
- plasmodium falciparum (isolate nf54) (マラリア病原虫)
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キーワード | IMMUNE SYSTEM / Malaria / Antibody |
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