タイトル | Polymorphic amyloid nanostructures of hormone peptides involved in glucose homeostasis display reversible amyloid formation. |
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ジャーナル・号・ページ | Nat Commun, Vol. 14, Page 4621-4621, Year 2023 |
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掲載日 | 2022年8月5日 (構造データの登録日) |
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著者 | Horvath, D. / Durvanger, Z. / K Menyhard, D. / Sulyok-Eiler, M. / Bencs, F. / Gyulai, G. / Horvath, P. / Taricska, N. / Perczel, A. |
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リンク | Nat Commun / PubMed:37528104 |
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手法 | X線回折 |
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解像度 | 0.9 - 1.75 Å |
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構造データ | PDB-8ang: Structure of the amyloid-forming peptide LYIQWL from Tc5b, grown from 30% ethanol 手法: X-RAY DIFFRACTION / 解像度: 1.5 Å PDB-8anh: Structure of the amyloid-forming peptide LYIQWL from Tc5b, grown from 30% acetonitrile 手法: X-RAY DIFFRACTION / 解像度: 1.25 Å PDB-8ani: Structure of the amyloid-forming peptide LYIQWL from Tc5b, grown from 10% ethanol 手法: X-RAY DIFFRACTION / 解像度: 1.35 Å PDB-8anj: Structure of the amyloid-forming peptide DFINWL from human GLP-2 手法: X-RAY DIFFRACTION / 解像度: 1.55 Å PDB-8ank: Structure of the amyloid-forming peptide pEFIAWL from human GLP-1 手法: X-RAY DIFFRACTION / 解像度: 1.3 Å PDB-8anl: Structure of the amyloid-forming peptide LFIEWL from exendin-4, grown from water 手法: X-RAY DIFFRACTION / 解像度: 1.75 Å PDB-8anm: Structure of the amyloid-forming peptide LYIQWL from Tc5b, grown from water 手法: X-RAY DIFFRACTION / 解像度: 0.9 Å PDB-8ann: Structure of the amyloid-forming peptide LFIEWL from exendin-4, grown from acetonitrile / water 手法: X-RAY DIFFRACTION / 解像度: 1.24 Å PDB-8onq: Structure of the amyloid-forming peptide Ac-EFIAWL from human GLP-1 手法: X-RAY DIFFRACTION / 解像度: 1.5 Å |
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化合物 | |
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由来 | - synthetic construct (人工物)
- homo sapiens (ヒト)
- heloderma suspectum (爬虫類)
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キーワード | PROTEIN FIBRIL / amyloid |
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