EMDB/PDB/SASBDBから引用されている文献のデータベース

キーワード
構造解析手法	All X線回折 NMR 電子顕微鏡小角散乱中性子線回折線維回折粉末回折赤外分光 EPR FRET 理論モデルハイブリッド
著者・登録者
ジャーナル
IF	>30 >20 >10 >5 all

タイトル	A structural expose of noncanonical molecular reactivity within the protein tyrosine phosphatase WPD loop.
ジャーナル・号・ページ	Nat Commun, Vol. 13, Page 2231-2231, Year 2022
掲載日	2021年5月1日 (構造データの登録日)
著者	Wang, H. / Perera, L. / Jork, N. / Zong, G. / Riley, A.M. / Potter, B.V.L. / Jessen, H.J. / Shears, S.B.
リンク	Nat Commun / PubMed:35468885
手法	X線回折
解像度	1.65 - 1.95 Å
構造データ	PDB-7mod: Crystal Structure of Arabidopsis thaliana Plant and Fungi Atypical Dual Specificity Phosphatase 1(AtPFA-DSP1 ) Cys150Ser in Complex with Phosphate in Conformation A (Pi(A)) 手法: X-RAY DIFFRACTION / 解像度: 1.65 Å PDB-7moe: Crystal Structure of Arabidopsis thaliana Plant and Fungi Atypical Dual Specificity Phosphatase 1(AtPFA-DSP1)Cys150Ser in complex with 5-diphosphoinositol 1,2,3,4,6-pentakisphosphate (5-InsP7) 手法: X-RAY DIFFRACTION / 解像度: 1.7 Å PDB-7mof: Crystal Structure of Arabidopsis thaliana Plant and Fungi Atypical Dual Specificity Phosphatase 1(AtPFA-DSP1 ) Cys150Ser in complex with 6-diphosphoinositol 1,2,3,4,5-pentakisphosphate 6-InsP7 手法: X-RAY DIFFRACTION / 解像度: 1.95 Å PDB-7mog: Crystal Structure of Arabidopsis thaliana Plant and Fungi Atypical Dual Specificity Phosphatase 1(AtPFA-DSP1 ) Cys150Ser in complex with 5-PCF2 Am-InsP5, an analogue of 5-InsP7 手法: X-RAY DIFFRACTION / 解像度: 1.8 Å PDB-7moh: Crystal Structure of Arabidopsis thaliana Plant and Fungi Atypical Dual Specificity Phosphatase 1(AtPFA-DSP1 ) Cys150Ser in complex with 5-diphosphoinositol 1,3,4,6-tetrakisphosphate (5PP-InsP4) and phosphate in conformation B (Pi(B)) 手法: X-RAY DIFFRACTION / 解像度: 1.9 Å PDB-7moi: Crystal Structure of Arabidopsis thaliana Plant and Fungi Atypical Dual Specificity Phosphatase 1(AtPFA-DSP1 ) Cys150Ser in complex with Phenyl Phosphate 手法: X-RAY DIFFRACTION / 解像度: 1.8 Å PDB-7moj: Crystal Structure of Arabidopsis thaliana Plant and Fungi Atypical Dual Specificity Phosphatase 1(AtPFA-DSP1 ) Cys150Ser in complex with a metaphosphate intermediate 手法: X-RAY DIFFRACTION / 解像度: 1.9 Å PDB-7mok: Crystal Structure of Arabidopsis thaliana Plant and Fungi Atypical Dual Specificity Phosphatase 1(AtPFA-DSP1 ) in Complex with Phosphate in Conformation A (Pi(A)) 手法: X-RAY DIFFRACTION / 解像度: 1.85 Å PDB-7mol: Crystal Structure of Arabidopsis thaliana Plant and Fungi Atypical Dual Specificity Phosphatase 1(AtPFA-DSP1 ) in complex with phosphate in conformation B (Pi(B)) 手法: X-RAY DIFFRACTION / 解像度: 1.9 Å PDB-7mom: Crystal Structure of Arabidopsis thaliana Plant and Fungi Atypical Dual Specificity Phosphatase 1(AtPFA-DSP1 ) in complex with a metaphosphate intermediate 手法: X-RAY DIFFRACTION / 解像度: 1.7 Å
化合物	ChemComp-PO4: PHOSPHATE ION / ホスファ-ト ChemComp-HOH: WATER ChemComp-I7P: (1r,2R,3S,4s,5R,6S)-2,3,4,5,6-pentakis(phosphonooxy)cyclohexyl trihydrogen diphosphate / D-myo-イノシト-ル1,2,3,4,6-ペンタキスりん酸5-二りん酸 ChemComp-ZKS: (1R,2R,3R,4R,5R,6S)-2,3,4,5,6-pentakis(phosphonooxy)cyclohexyl trihydrogen diphosphate / D-myo-イノシト-ル1,2,3,4,5-ペンタキスりん酸6-二りん酸 ChemComp-IHP: INOSITOL HEXAKISPHOSPHATE / フィチン酸 ChemComp-KDJ: (1,1-difluoro-2-oxo-2-{[(1s,2R,3S,4s,5R,6S)-2,3,4,5,6-pentakis(phosphonooxy)cyclohexyl]amino}ethyl)phosphonic acid ChemComp-U6J: (1r,2R,3S,4r,5R,6S)-4-hydroxy-2,3,5,6-tetrakis(phosphonooxy)cyclohexyl trihydrogen diphosphate / D-myo-イノシト-ル1,3,4,6-テトラりん酸5-二りん酸 ChemComp-HPS: PHENYL DIHYDROGEN PHOSPHATE / りん酸フェニル ChemComp-PO3: PHOSPHITE ION / ホスファイト ChemComp-BME: BETA-MERCAPTOETHANOL / 2-メルカプトエタノ-ル ChemComp-EPE: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID / HEPES / pH緩衝剤*YM
由来	arabidopsis thaliana (シロイヌナズナ)
キーワード	HYDROLASE / inositol / inositol pyrophosphate / TRANSFERASE / cell-signaling / phosphatase / substrate recognition / reaction mechanism / intermediate / phosphate / metaphosphate / molecular dynamic simulation / self-activation / catalytic water