EMDB/PDB/SASBDBから引用されている文献のデータベース

キーワード
構造解析手法	All X線回折 NMR 電子顕微鏡小角散乱中性子線回折線維回折粉末回折赤外分光 EPR FRET 理論モデルハイブリッド
著者・登録者
ジャーナル
IF	>30 >20 >10 >5 all

タイトル	Selective inhibition reveals the regulatory function of DYRK2 in protein synthesis and calcium entry.
ジャーナル・号・ページ	Elife, Vol. 11, Year 2022
掲載日	2020年11月10日 (構造データの登録日)
著者	Wei, T. / Wang, J. / Liang, R. / Chen, W. / Chen, Y. / Ma, M. / He, A. / Du, Y. / Zhou, W. / Zhang, Z. ...Wei, T. / Wang, J. / Liang, R. / Chen, W. / Chen, Y. / Ma, M. / He, A. / Du, Y. / Zhou, W. / Zhang, Z. / Zeng, X. / Wang, C. / Lu, J. / Guo, X. / Chen, X.W. / Wang, Y. / Tian, R. / Xiao, J. / Lei, X.
リンク	Elife / PubMed:35439114
手法	X線回折
解像度	2.194 - 3.29 Å
構造データ	PDB-7dg4: The co-crystal structure of DYRK2 with a small molecule inhibitor 6 手法: X-RAY DIFFRACTION / 解像度: 2.58 Å PDB-7dh9: The co-crystal structure of DYRK2 with a small molecule inhibitor 7 手法: X-RAY DIFFRACTION / 解像度: 2.194 Å PDB-7dhc: The co-crystal structure of DYRK2 with a small molecule inhibitor 10 手法: X-RAY DIFFRACTION / 解像度: 2.592 Å PDB-7dhh: The co-crystal structure of DYRK2 with a small molecule inhibitor 19 手法: X-RAY DIFFRACTION / 解像度: 2.486 Å PDB-7dhk: The co-crystal structure of DYRK2 with a small molecule inhibitor 13 手法: X-RAY DIFFRACTION / 解像度: 2.341 Å PDB-7dhn: The co-crystal structure of DYRK2 with a small molecule inhibitor 20 手法: X-RAY DIFFRACTION / 解像度: 2.38 Å PDB-7dho: The co-crystal structure of DYRK2 with a small molecule inhibitor 14 手法: X-RAY DIFFRACTION / 解像度: 3.29 Å PDB-7dhv: The co-crystal structure of DYRK2 with a small molecule inhibitor 8 手法: X-RAY DIFFRACTION / 解像度: 2.679 Å PDB-7djo: The co-crystal structure of DYRK2 with a small molecule inhibitor 17 手法: X-RAY DIFFRACTION / 解像度: 2.499 Å PDB-7dl6: The co-crystal structure of DYRK2 with a small molecule inhibitor 18 手法: X-RAY DIFFRACTION / 解像度: 2.648 Å
化合物	ChemComp-H5R: 2,7-dimethoxy-9-(piperidin-4-ylmethylsulfanyl)acridine ChemComp-HOH: WATER ChemComp-H7F: [2,7-dimethoxy-9-(piperidin-4-ylmethylsulfanyl)acridin-4-yl]methanol ChemComp-H99: 4-[bis(fluoranyl)methyl]-2,7-dimethoxy-9-(piperidin-4-ylmethylsulfanyl)acridine ChemComp-H7L: [9-(azetidin-3-ylmethylsulfanyl)-2,7-dimethoxy-acridin-4-yl]methanol ChemComp-H7O: 2-methoxy-7-phenylmethoxy-9-(piperidin-4-ylmethylsulfanyl)acridine ChemComp-H7R: 7-methoxy-2-methylsulfanyl-9-(piperidin-4-ylmethylsulfanyl)-[1,3]thiazolo[5,4-b]quinoline ChemComp-H7U: 2-methoxy-9-(piperidin-4-ylmethylsulfanyl)-7-propan-2-yloxy-acridine ChemComp-H7X: 2,7-dimethoxy-9-(piperidin-4-ylmethylsulfanyl)acridine-4-carboxylic acid ChemComp-H80: [2,7-dimethoxy-9-[[(3S)-pyrrolidin-3-yl]methylsulfanyl]acridin-4-yl]methanol ChemComp-H96: [2,7-dimethoxy-9-[[(3R)-pyrrolidin-3-yl]methylsulfanyl]acridin-4-yl]methanol
由来	homo sapiens (ヒト)
キーワード	CELL CYCLE / kinase / inhibitor