タイトル | Structural basis for the hyperthermostability of an archaeal enzyme induced by succinimide formation. |
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ジャーナル・号・ページ | Biophys. J., Vol. 120, Page 3732-3746, Year 2021 |
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掲載日 | 2020年9月21日 (構造データの登録日) |
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著者 | Dongre, A.V. / Das, S. / Bellur, A. / Kumar, S. / Chandrashekarmath, A. / Karmakar, T. / Balaram, P. / Balasubramanian, S. / Balaram, H. |
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リンク | Biophys. J. / PubMed:34302792 |
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手法 | X線回折 |
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解像度 | 1.67 - 2.29 Å |
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構造データ | PDB-7d40: Crystal structure of GATase subunit of Methanocaldococcus jannaschii GMP synthetase 手法: X-RAY DIFFRACTION / 解像度: 1.67 Å PDB-7d95: Crystal structure of acivicin-bound GATase subunit of Methanocaldococcus jannaschii GMP synthetase 手法: X-RAY DIFFRACTION / 解像度: 1.67 Å PDB-7d96: Crystal structure of D110G mutant of GATase subunit of Methanocaldococcus jannaschii GMP synthetase 手法: X-RAY DIFFRACTION / 解像度: 2.29 Å PDB-7d97: Crystal structure of N109P mutant of GATase subunit of Methanocaldococcus jannaschii GMP synthetase 手法: X-RAY DIFFRACTION / 解像度: 1.89 Å |
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化合物 | |
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由来 | ![](img/tx_archaea.gif) ![](img/tx_thermo.gif) methanocaldococcus jannaschii dsm 2661 (メタン生成菌)
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キーワード | LIGASE (リガーゼ) / Class I glutamine amidotransferase / Deamidation (脱アミド) / Purine Synthesis / glutamine hydrolysis / Succinimide (スクシンイミド) / hyperthermostable glutamine amidotransferase / acivicin bound GATase / GATase_D110G / GATase_N109P |
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