タイトル | Stepwise Post-glycosylation Modification of Sugar Moieties in Kanamycin Biosynthesis. |
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ジャーナル・号・ページ | Chembiochem, Vol. 22, Page 1668-1675, Year 2021 |
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掲載日 | 2020年7月20日 (構造データの登録日) |
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著者 | Kudo, F. / Kitayama, Y. / Miyanaga, A. / Numakura, M. / Eguchi, T. |
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リンク | Chembiochem / PubMed:33403742 |
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手法 | X線回折 |
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解像度 | 2 - 2.5 Å |
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構造データ | PDB-7cl2: The crystal structure of KanJ 手法: X-RAY DIFFRACTION / 解像度: 2 Å PDB-7cl3: The crystal structure of KanJ in complex with kanamycin B 手法: X-RAY DIFFRACTION / 解像度: 2.2 Å PDB-7cl4: The crystal structure of KanJ in complex with N-oxalylglycine 手法: X-RAY DIFFRACTION / 解像度: 2.25 Å PDB-7cl5: The crystal structure of KanJ in complex with kanamycin B and N-oxalylglycine 手法: X-RAY DIFFRACTION / 解像度: 2.5 Å PDB-7cl6: The crystal structure of KanJ in complex with neamine and N-oxalylglycine 手法: X-RAY DIFFRACTION / 解像度: 2.44 Å |
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化合物 | ChemComp-9CS: (1R,2S,3S,4R,6S)-4,6-DIAMINO-3-[(3-AMINO-3-DEOXY-ALPHA-D-GLUCOPYRANOSYL)OXY]-2-HYDROXYCYCLOHEXYL 2,6-DIAMINO-2,6-DIDEOXY-ALPHA-D-GLUCOPYRANOSIDE / カナマイシンB / 抗生剤*YM
ChemComp-XXX: (1R,2R,3S,4R,6S)-4,6-diamino-2,3-dihydroxycyclohexyl 2,6-diamino-2,6-dideoxy-alpha-D-glucopyranoside / ネアミン / 抗生剤*YM
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由来 | streptomyces kanamyceticus (カナマイシン生産菌)
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キーワード | OXIDOREDUCTASE / Dioxygenase / kanamycin biosynthesis |
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