EMDB/PDB/SASBDBから引用されている文献のデータベース

キーワード
構造解析手法	All X線回折 NMR 電子顕微鏡小角散乱中性子線回折線維回折粉末回折赤外分光 EPR FRET 理論モデルハイブリッド
著者・登録者
ジャーナル
IF	>30 >20 >10 >5 all

タイトル	An on-demand, drop-on-drop method for studying enzyme catalysis by serial crystallography.
ジャーナル・号・ページ	Nat Commun, Vol. 12, Page 4461-4461, Year 2021
掲載日	2021年1月10日 (構造データの登録日)
著者	Butryn, A. / Simon, P.S. / Aller, P. / Hinchliffe, P. / Massad, R.N. / Leen, G. / Tooke, C.L. / Bogacz, I. / Kim, I.S. / Bhowmick, A. ...Butryn, A. / Simon, P.S. / Aller, P. / Hinchliffe, P. / Massad, R.N. / Leen, G. / Tooke, C.L. / Bogacz, I. / Kim, I.S. / Bhowmick, A. / Brewster, A.S. / Devenish, N.E. / Brem, J. / Kamps, J.J.A.G. / Lang, P.A. / Rabe, P. / Axford, D. / Beale, J.H. / Davy, B. / Ebrahim, A. / Orlans, J. / Storm, S.L.S. / Zhou, T. / Owada, S. / Tanaka, R. / Tono, K. / Evans, G. / Owen, R.L. / Houle, F.A. / Sauter, N.K. / Schofield, C.J. / Spencer, J. / Yachandra, V.K. / Yano, J. / Kern, J.F. / Orville, A.M.
リンク	Nat Commun / PubMed:34294694
手法	X線回折
解像度	1.45 - 1.65 Å
構造データ	PDB-7bh3: XFEL structure of CTX-M-15 resting state 手法: X-RAY DIFFRACTION / 解像度: 1.6 Å PDB-7bh4: XFEL structure of apo CTX-M-15 after mixing for 0.7 sec with ertapenem using a piezoelectric injector (PolyPico) 手法: X-RAY DIFFRACTION / 解像度: 1.55 Å PDB-7bh5: XFEL structure of the ertapenem-derived CTX-M-15 acylenzyme after mixing for 2 sec using a piezoelectric injector (PolyPico) 手法: X-RAY DIFFRACTION / 解像度: 1.55 Å PDB-7bh6: Room temperature, serial X-ray structure of CTX-M-15 collected on fixed target chips at Diamond Light Source I24 手法: X-RAY DIFFRACTION / 解像度: 1.65 Å PDB-7bh7: Room temperature, serial X-ray structure of the ertapenem-derived acylenzyme of CTX-M-15 (10 min soak) collected on fixed target chips at Diamond Light Source I24 手法: X-RAY DIFFRACTION / 解像度: 1.65 Å PDB-7bhk: Crystal structure of hen egg white lysozyme using drop-on-drop SFX method. 手法: X-RAY DIFFRACTION / 解像度: 1.45 Å PDB-7bhl: Crystal structure of hen egg white lysozyme using drop-on-drop SFX method - 0.2 s mixing with N-acetyl-D-glucosamine. 手法: X-RAY DIFFRACTION / 解像度: 1.45 Å PDB-7bhm: Crystal structure of hen egg white lysozyme using drop-on-drop SFX method - 0.7 s mixing with N-acetyl-D-glucosamine. 手法: X-RAY DIFFRACTION / 解像度: 1.45 Å PDB-7bhn: Crystal structure of hen egg white lysozyme using drop-on-drop SFX method - 2 s mixing with N-acetyl-D-glucosamine. 手法: X-RAY DIFFRACTION / 解像度: 1.45 Å
化合物	ChemComp-SO4: SULFATE ION / 硫酸ジアニオン ChemComp-CL: Unknown entry / クロリド ChemComp-HOH: WATER ChemComp-TVE: (2~{S},3~{R},4~{R})-3-[5-[(3-carboxyphenyl)carbamoyl]pyrrolidin-3-yl]sulfanyl-4-methyl-5-[(2~{S},3~{R})-3-oxidanyl-1-oxidanylidene-butan-2-yl]-3,4-dihydro-2~{H}-pyrrole-2-carboxylic acid ChemComp-NA: Unknown entry / ナトリウムカチオン ChemComp-NDG: 2-acetamido-2-deoxy-alpha-D-glucopyranose / N-アセチル-α-D-グルコサミン
由来	klebsiella pneumoniae (肺炎桿菌) gallus gallus (ニワトリ)
キーワード	ANTIMICROBIAL PROTEIN / serial crystallography / beta-lactamase / antibiotic / ertapenem / XFEL / HYDROLASE / lysozyme / SFX