EMDB/PDB/SASBDBから引用されている文献のデータベース

キーワード
構造解析手法	All X線回折 NMR 電子顕微鏡小角散乱中性子線回折線維回折粉末回折赤外分光 EPR FRET 理論モデルハイブリッド
著者・登録者
ジャーナル
IF	>30 >20 >10 >5 all

タイトル	Structural Insights into Schistosoma mansoni Carbonic Anhydrase (SmCA) Inhibition by Selenoureido-Substituted Benzenesulfonamides.
ジャーナル・号・ページ	J. Med. Chem., Vol. 64, Page 10418-10428, Year 2021
掲載日	2019年2月18日 (構造データの登録日)
著者	Angeli, A. / Ferraroni, M. / Da'dara, A.A. / Selleri, S. / Pinteala, M. / Carta, F. / Skelly, P.J. / Supuran, C.T.
リンク	J. Med. Chem. / PubMed:34232641
手法	X線回折
解像度	1.4 - 2.28 Å
構造データ	PDB-6qqm: Crystal structure of the alpha carbonic anhydrase from Schistosoma mansoni 手法: X-RAY DIFFRACTION / 解像度: 1.75 Å PDB-7bfa: 4-(2-(3-(4-iodophenyl)thioureido)ethyl)benzenesulfonamide in complex with Carbonic Anhydrase II 手法: X-RAY DIFFRACTION / 解像度: 1.6 Å PDB-7bg5: 4-(2-(3-(4-iodophenyl)ureido)ethyl)benzenesulfonamide in complex with Carbonic Anhydrase II 手法: X-RAY DIFFRACTION / 解像度: 1.428 Å PDB-7bhh: 4-(2-(3-(4-iodophenyl)selenoureido)ethyl)benzenesulfonamide in complex with Carbonic Anhydrase II 手法: X-RAY DIFFRACTION / 解像度: 1.4 Å PDB-7bm4: Crystal structure of alpha Carbonic anhydrase from Schistosoma mansoni bound to 1-(4-fluorophenyl)-3-(4-sulphamoylphenyl)selenourea 手法: X-RAY DIFFRACTION / 解像度: 1.6 Å PDB-7nex: Crystal structure of alpha Carbonic anhydrase from Schistosoma mansoni bound to 1-(4-fluorophenyl)-3-(4-sulfamoylph enyl)thiourea 手法: X-RAY DIFFRACTION / 解像度: 1.81 Å PDB-7ng1: Crystal structure of alpha Carbonic anhydrase from Schistoso ma mansoni bound to 1-(4-iodophenyl)-3-[2-(4-sulfamoylphenyl)ethyl]selenourea 手法: X-RAY DIFFRACTION / 解像度: 1.67 Å PDB-7nwy: Crystal structure of alpha carbonic anhydrase from schistosoma mansoni with 4-(3-(4-fluorophenyl)ureido)benzenesulfonamide 手法: X-RAY DIFFRACTION / 解像度: 1.807 Å PDB-7o2s: Crystal structure of a tetrameric form of Carbonic anhydrase from Schistosoma mansoni 手法: X-RAY DIFFRACTION / 解像度: 2.28 Å PDB-7o48: Crystal structure of carbonic anhydrase from schistosoma mansoni with 4-(2-(3-(4-iodophenyl)thioureido)ethyl)benzenesulfonamide 手法: X-RAY DIFFRACTION / 解像度: 2.0 Å PDB-7oa1: Crystal structure of alfa carbonic anhydrase from Schistosoma mansoni with 4-(2-(3-(4-iodophenyl)ureido)ethyl)benzenesulfonamide 手法: X-RAY DIFFRACTION / 解像度: 2.0 Å
化合物	ChemComp-ZN: Unknown entry ChemComp-GOL: GLYCEROL / グリセロ-ル ChemComp-NAG: 2-acetamido-2-deoxy-beta-D-glucopyranose / N-アセチル-β-D-グルコサミン ChemComp-HOH: WATER ChemComp-TKE: 1-(4-iodophenyl)-3-[2-(4-sulfamoylphenyl)ethyl]thiourea ChemComp-TKQ: 1-(4-iodophenyl)-3-[2-(4-sulfamoylphenyl)ethyl]urea ChemComp-TN8: ~{N}'-(4-iodophenyl)-~{N}-[2-(4-sulfamoylphenyl)ethyl]carbamimidoselenoic acid ChemComp-U3N: 1-(4-fluorophenyl)-3-(4-sulfamoylphenyl)selenourea ChemComp-8JS: 4-{[(4-fluorophenyl)carbamothioyl]amino}benzene-1-sulfonamide ChemComp-WWZ: 4-{[(4-fluorophenyl)carbamoyl]amino}benzenesulfonamide / SLC-0111
由来	schistosoma mansoni (マンソン住血吸虫) homo sapiens (ヒト)
キーワード	LYASE / carbonic anhydrase II / inhibitors / sulfonamide / inhibitor / carbonic anhydrase / inibitor / organoseleno / schistosoma mansoni / metalloenzyme / neglected diseases / complex