タイトル | Siroheme synthase orients substrates for dehydrogenase and chelatase activities in a common active site. |
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ジャーナル・号・ページ | Nat Commun, Vol. 11, Page 864-864, Year 2020 |
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掲載日 | 2019年5月31日 (構造データの登録日) |
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著者 | Pennington, J.M. / Kemp, M. / McGarry, L. / Chen, Y. / Stroupe, M.E. |
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リンク | Nat Commun / PubMed:32054833 |
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手法 | X線回折 |
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解像度 | 1.82 - 2.76 Å |
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構造データ | PDB-6p5x: Sirohydrochlorin-bound S. typhimurium siroheme synthase 手法: X-RAY DIFFRACTION / 解像度: 1.97 Å PDB-6p5z: Cobalt-sirohydrochlorin-bound S. typhimurium siroheme synthase 手法: X-RAY DIFFRACTION / 解像度: 2.26 Å PDB-6p7c: D104A/S128A S. typhimurium siroheme synthase 手法: X-RAY DIFFRACTION / 解像度: 2.76 Å PDB-6p7d: D104N S. typhimurium siroheme synthase 手法: X-RAY DIFFRACTION / 解像度: 2.4 Å PDB-6pqz: P133G/S128A S. typhimurium siroheme synthase 手法: X-RAY DIFFRACTION / 解像度: 2.23 Å PDB-6pr0: P133H-S128A S. typhimurium siroheme synthase 手法: X-RAY DIFFRACTION / 解像度: 1.9 Å PDB-6pr1: R260A/S128A S. typhimurium siroheme synthase 手法: X-RAY DIFFRACTION / 解像度: 1.82 Å PDB-6pr2: R261A/S128A S. typhimurium siroheme synthase 手法: X-RAY DIFFRACTION / 解像度: 2.16 Å PDB-6pr3: D262A/S128A S. typhimurium siroheme synthase 手法: X-RAY DIFFRACTION / 解像度: 1.96 Å PDB-6pr4: D262N/S128A S. typhimurium siroheme synthase 手法: X-RAY DIFFRACTION / 解像度: 2.24 Å PDB-6ulu: D104A/S128A S. typhimurium siroheme synthase 手法: X-RAY DIFFRACTION / 解像度: 2.76 Å PDB-6veb: Precorrin-2-bound S128A S. typhimurium siroheme synthase 手法: X-RAY DIFFRACTION / 解像度: 2.55 Å |
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化合物 | ChemComp-SHN: 3,3',3'',3'''-[(7S,8S,12S,13S)-3,8,13,17-tetrakis(carboxymethyl)-8,13-dimethyl-7,8,12,13-tetrahydroporphyrin-2,7,12,18-tetrayl]tetrapropanoic acid
ChemComp-NAD: NICOTINAMIDE-ADENINE-DINUCLEOTIDE / NAD*YM
ChemComp-PQ2: 3,3',3'',3'''-[(7S,8S,12S,13S)-3,8,13,17-tetrakis(carboxymethyl)-8,13-dimethyl-7,8,12,13,20,24-hexahydroporphyrin-2,7,1
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由来 | - salmonella typhimurium (サルモネラ菌)
- salmonella enterica i (サルモネラ菌)
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キーワード | BIOSYNTHETIC PROTEIN / sirohydrochlorin / precorrin-2 / tetrapyrrole biosynthesis / CysG / TRANSFERASE / siroheme |
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