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-Structure paper
タイトル | Cryo-EM reveals the structural basis of long-range electron transport in a cytochrome-based bacterial nanowire. |
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ジャーナル・号・ページ | Commun Biol, Vol. 2, Page 219, Year 2019 |
掲載日 | 2019年6月19日 |
著者 | David J Filman / Stephen F Marino / Joy E Ward / Lu Yang / Zoltán Mester / Esther Bullitt / Derek R Lovley / Mike Strauss / |
PubMed 要旨 | Electrically conductive pili from species, termed bacterial nanowires, are intensely studied for their biological significance and potential in the development of new materials. Using cryo-electron ...Electrically conductive pili from species, termed bacterial nanowires, are intensely studied for their biological significance and potential in the development of new materials. Using cryo-electron microscopy, we have characterized nanowires from conductive pili preparations that are composed solely of head-to-tail stacked monomers of the six-heme C-type cytochrome OmcS. The unique fold of OmcS - closely wrapped around a continuous stack of hemes that can serve as an uninterrupted path for electron transport - generates a scaffold that supports the unbranched chain of hemes along the central axis of the filament. We present here, at 3.4 Å resolution, the structure of this cytochrome-based filament and discuss its possible role in long-range biological electron transport. |
リンク | Commun Biol / PubMed:31240257 / PubMed Central |
手法 | EM (らせん対称) |
解像度 | 3.4 Å |
構造データ | |
化合物 | ChemComp-HEC: ChemComp-MG: |
由来 |
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キーワード | PROTEIN FIBRIL / Conductive / filament / nanowire / SIX-HEME MULTIHEME C-TYPE CYTOCHROME |