EMDB/PDB/SASBDBから引用されている文献のデータベース

キーワード
構造解析手法	All X線回折 NMR 電子顕微鏡小角散乱中性子線回折線維回折粉末回折赤外分光 EPR FRET 理論モデルハイブリッド
著者・登録者
ジャーナル
IF	>30 >20 >10 >5 all

タイトル	Structural Analyses of Toll-like Receptor 7 Reveal Detailed RNA Sequence Specificity and Recognition Mechanism of Agonistic Ligands.
ジャーナル・号・ページ	Cell Rep, Vol. 25, Page 3371-3381.e5, Year 2018
掲載日	2018年4月28日 (構造データの登録日)
著者	Zhang, Z. / Ohto, U. / Shibata, T. / Taoka, M. / Yamauchi, Y. / Sato, R. / Shukla, N.M. / David, S.A. / Isobe, T. / Miyake, K. / Shimizu, T.
リンク	Cell Rep / PubMed:30566863
手法	X線回折
解像度	2 - 2.7 Å
構造データ	PDB-5zsa: Crystal structure of monkey TLR7 in complex with IMDQ and UUUUUU 手法: X-RAY DIFFRACTION / 解像度: 2.5 Å PDB-5zsb: Crystal structure of monkey TLR7 in complex with IMDQ and AAUUAA 手法: X-RAY DIFFRACTION / 解像度: 2.7 Å PDB-5zsc: Crystal structure of monkey TLR7 in complex with IMDQ and CCUUCC 手法: X-RAY DIFFRACTION / 解像度: 2.2 Å PDB-5zsd: Crystal structure of monkey TLR7 in complex with IMDQ and GGUUGG 手法: X-RAY DIFFRACTION / 解像度: 2.603 Å PDB-5zse: Crystal structure of monkey TLR7 in complex with IMDQ and GGUCCC 手法: X-RAY DIFFRACTION / 解像度: 2.201 Å PDB-5zsf: Crystal structure of monkey TLR7 in complex with imiquimod 手法: X-RAY DIFFRACTION / 解像度: 2.1 Å PDB-5zsg: Crystal structure of monkey TLR7 in complex with gardiquimod 手法: X-RAY DIFFRACTION / 解像度: 2.3 Å PDB-5zsh: Crystal structure of monkey TLR7 in complex with CL075 手法: X-RAY DIFFRACTION / 解像度: 2.6 Å PDB-5zsi: Crystal structure of monkey TLR7 in complex with CL097 手法: X-RAY DIFFRACTION / 解像度: 2.7 Å PDB-5zsj: Crystal structure of monkey TLR7 in complex with GS9620 手法: X-RAY DIFFRACTION / 解像度: 2.4 Å PDB-5zsl: Crystal structure of monkey TLR7 in complex with GGUUGG 手法: X-RAY DIFFRACTION / 解像度: 2.3 Å PDB-5zsm: Crystal structure of monkey TLR7 in complex with GGUCCC 手法: X-RAY DIFFRACTION / 解像度: 2.5 Å PDB-5zsn: Crystal structure of monkey TLR7 in complex with AAUUAA 手法: X-RAY DIFFRACTION / 解像度: 2.4 Å PDB-6if5: Crystal structure of monkey TLR7 in complex with 2',3'-cGMP (Guanosine 2',3'-cyclic phosphate) 手法: X-RAY DIFFRACTION / 解像度: 2.0 Å
化合物	ChemComp-NAG: 2-acetamido-2-deoxy-beta-D-glucopyranose / N-アセチル-β-D-グルコサミン ChemComp-IDQ: 1-[[4-(aminomethyl)phenyl]methyl]-2-butyl-imidazo[4,5-c]quinolin-4-amine / 1-(4-(アミノメチル)ベンジル)-2-ブチル-1H-イミダゾ[4,5-c]キノリン-4-アミン ChemComp-SO4: SULFATE ION / 硫酸ジアニオン ChemComp-HOH: WATER ChemComp-6T0: 1-(2-methylpropyl)imidazo[4,5-c]quinolin-4-amine / イミキモド / 薬剤YM ChemComp-9K3: 1-{4-amino-2-[(ethylamino)methyl]-1H-imidazo[4,5-c]quinolin-1-yl}-2-methylpropan-2-ol / ガルジキモド ChemComp-L07: 2-propyl[1,3]thiazolo[4,5-c]quinolin-4-amine / 2-プロピルチアゾロ[4,5-c]キノリン-4-アミン ChemComp-C09: 2-(ethoxymethyl)-1H-imidazo[4,5-c]quinolin-4-amine / CL-097 ChemComp-9JR: 4-azanyl-2-butoxy-8-[[3-(pyrrolidin-1-ylmethyl)phenyl]methyl]-5,7-dihydropteridin-6-one / GS-9620 ChemComp-9K9: 2-amino-9-[(2S,3aR,4R,6R,6aR)-2-hydroxy-6-(hydroxymethyl)-2-oxotetrahydro-2H-2lambda~5~-furo[3,4-d][1,3,2]dioxaphosphol-4-yl]-3,9-dihydro-6H-purin-6-one / 2′,3′-cGMP ChemComp-PO4: PHOSPHATE ION / ホスファ-ト ChemComp-ACK: 2',3'- cyclic AMP / 2′,3′-cAMP ChemComp-23G*: GUANOSINE-5'-PHOSPHATE-2',3'-CYCLIC PHOSPHATE
由来	macaca mulatta (アカゲザル) synthetic construct (人工物)
キーワード	IMMUNE SYSTEM / Innate immunity Toll-like receptors