タイトル | Multi-domain utilization by TUT4 and TUT7 in control of let-7 biogenesis. |
---|
ジャーナル・号・ページ | Nat. Struct. Mol. Biol., Vol. 24, Page 658-665, Year 2017 |
---|
掲載日 | 2017年5月30日 (構造データの登録日) |
---|
著者 | Faehnle, C.R. / Walleshauser, J. / Joshua-Tor, L. |
---|
リンク | Nat. Struct. Mol. Biol. / PubMed:28671666 |
---|
手法 | X線回折 |
---|
解像度 | 2.298 - 2.614 Å |
---|
構造データ | PDB-5w0b: Structure of human TUT7 catalytic module (CM) 手法: X-RAY DIFFRACTION / 解像度: 2.614 Å PDB-5w0m: Structure of human TUT7 catalytic module (CM) in complex with U5 RNA 手法: X-RAY DIFFRACTION / 解像度: 2.298 Å PDB-5w0n: Structure of human TUT7 catalytic module (CM) in complex with UMPNPP and U2 RNA 手法: X-RAY DIFFRACTION / 解像度: 2.497 Å PDB-5w0o: Structure of human TUT7 catalytic module (CM) in complex with dsRNA 手法: X-RAY DIFFRACTION / 解像度: 2.488 Å |
---|
化合物 | ChemComp-2KH: 5'-O-[(S)-hydroxy{[(S)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]uridine
ChemComp-UPU: [(2R,3S,4R,5R)-5-(2,4-DIOXO-3,4-DIHYDROPYRIMIDIN-1(2H)-YL)-3,4-DIHYDROXYTETRAHYDROFURAN-2-YL]METHYL (2R,3S,4R,5R)-5-(2,4-DIOXO-3,4-DIHYDROPYRIMIDIN-1(2H)-YL)-4-HYDROXY-2-(HYDROXYMETHYL)TETRAHYDROFURAN-3-YL HYDROGEN (S)-PHOSPHATE / 3′-O-(5′-ウリジリル)ウリジン
|
---|
由来 | - homo sapiens (ヒト)
- synthetic construct (人工物)
|
---|
キーワード | TRANSFERASE / terminal uridyltransferase / TUTase / TRANSFERASE/RNA / TRANSFERASE-RNA complex |
---|